Suppr超能文献

阿尔茨海默病和多发梗死性痴呆中的听觉长潜伏期事件相关电位

Auditory long latency event-related potentials in Alzheimer's disease and multi-infarct dementia.

作者信息

Neshige R, Barrett G, Shibasaki H

机构信息

Department of Internal Medicine, Saga Medical School, Japan.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Sep;51(9):1120-5. doi: 10.1136/jnnp.51.9.1120.

Abstract

An auditory discrimination paradigm was employed to elicit event-related brain potentials in 13 patients with Alzheimer's disease and 14 patients with multi-infarct dementia. The P300 latency was significantly prolonged in 12 patients with dementia compared with age-matched controls and showed a significant negative correlation with the score of Wechsler Adult Intelligence Scale (WAIS), especially with that of Digit Span subtest. There was no disease specificity. After physostigmine treatment, P300 latency decreased and WAIS score increased in 6 among 10 cases.

摘要

采用听觉辨别范式,对13例阿尔茨海默病患者和14例多发梗死性痴呆患者进行事件相关脑电位检测。与年龄匹配的对照组相比,12例痴呆患者的P300潜伏期显著延长,且与韦氏成人智力量表(WAIS)得分呈显著负相关,尤其是与数字广度分测验得分。不存在疾病特异性。在毒扁豆碱治疗后,10例中有6例的P300潜伏期缩短,WAIS得分提高。

相似文献

6
Improved detection of auditory P3 abnormality in dementia using a variety of stimuli.
Acta Neurol Scand. 1995 Jul;92(1):96-101. doi: 10.1111/j.1600-0404.1995.tb00474.x.
8
[P300 and dementia: diagnostic relevance. I].
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1990 Sep;21(3):137-44.

引用本文的文献

5
Electric field distribution of event-related potentials in stroke patients.
Brain Topogr. 1996 Spring;8(3):279-84. doi: 10.1007/BF01184785.
10
Screening for hearing impairment in the elderly: rationale and strategy.
J Gen Intern Med. 1991 May-Jun;6(3):249-58. doi: 10.1007/BF02598971.

本文引用的文献

5
Lecithin does not affect EEG spectral analysis or P300 in Alzheimer disease.
Neurology. 1982 Nov;32(11):1260-6. doi: 10.1212/wnl.32.11.1260.
6
The effects of age on human event-related potentials.
Psychophysiology. 1984 May;21(3):312-25. doi: 10.1111/j.1469-8986.1984.tb02941.x.
7
P300 latency correlates with digit span.
Psychophysiology. 1983 Nov;20(6):665-9. doi: 10.1111/j.1469-8986.1983.tb00936.x.
10

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验