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新型冠状病毒肺炎的流行病学和临床特征;一篇叙述性综述

Epidemiological and Clinical Aspects of COVID-19; a Narrative Review.

作者信息

Kolifarhood Goodarz, Aghaali Mohammad, Mozafar Saadati Hossein, Taherpour Niloufar, Rahimi Sajjad, Izadi Neda, Hashemi Nazari Seyed Saeed

机构信息

Department of Epidemiology, School of Public Health & Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Student Research Committee, Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Arch Acad Emerg Med. 2020 Apr 1;8(1):e41. eCollection 2020.

Abstract

There are significant misconceptions and many obstacles in the way of illuminating the epidemiological and clinical aspects of COVID-19 as a new emerging epidemic. In addition, usefulness of some evidence published in the context of the recent epidemic for decision making in clinic as well as public health is questionable. However, misinterpreting or ignoring strong evidence in clinical practice and public health probably results in less effective and somehow more harmful decisions for individuals as well as subgroups in general populations of countries in the initial stages of this epidemic. Accordingly, our narrative review appraised epidemiological and clinical aspects of the disease including genetic diversity of coronavirus genus, mode of transmission, incubation period, infectivity, pathogenicity, virulence, immunogenicity, diagnosis, surveillance, clinical case management and also successful measures for preventing its spread in some communities.

摘要

作为一种新出现的流行病,在阐明新冠病毒病的流行病学和临床特征方面存在重大误解和诸多障碍。此外,近期疫情背景下发表的一些证据对临床和公共卫生决策的实用性也值得怀疑。然而,在临床实践和公共卫生中误解或忽视有力证据,可能会导致在疫情初期对各国普通人群中的个体以及亚群体做出效果较差且在某种程度上更有害的决策。因此,我们的叙述性综述评估了该疾病的流行病学和临床特征,包括冠状病毒属的基因多样性、传播方式、潜伏期、传染性、致病性、毒力、免疫原性、诊断、监测、临床病例管理以及在一些社区预防其传播的成功措施。

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