Zwart Lennaert Ar, Jansen René Wmm, Ruiter Jacob H, Germans Tjeerd, Simsek Suat, Hemels Martin Ew
Department of Geriatric Medicine, North West Clinics, Wilhelminalaan, Alkmaar, the Netherlands.
Department of Geriatric Medicine, Dijklander Hospital, Maelsonstraat, Hoorn, the Netherlands.
J Geriatr Cardiol. 2020 Mar;17(3):149-154. doi: 10.11909/j.issn.1671-5411.2020.03.007.
To determine the diagnostic yield of repeated screening for atrial fibrillation (AF) among geriatric patients.
A pragmatic prospective cohort study into applying opportunistic screening for AF with a handheld single lead ECG device (SLD) in a geriatric cohort. Consecutive patients of 65 years old and older visiting the geriatric outpatient clinic were eligible for inclusion. A 12 lead ECG was performed, followed by measurements with the SLD during every visit to the geriatric outpatient clinic. A frailty index was based on the accumulation of deficits model.
478 patients were eligible. Patients were excluded if they did not give informed consent (17 patients), had a pacemaker or implantable cardioverter defibrillator (20 patients), or had incomplete medical files (two patients). After exclusion, 439 patients participated in this study. The mean age was 78 years (range 65 to 100 years), 54% were female. AF was known in 89 patients (20%), first detected on the baseline ECG in four patients (1%) and first detected with the SLD in 20 patients (5%) during follow up visits. Sensitivity of the SLD was 90.0%, specificity 99.0%, negative predictive value 99.7%, and positive predictive value 73.5%. Most patients (82%) with AF were frail and 53% were severely frail.
Repeated screening in geriatric patients has a five times higher diagnostic yield than usual care. It was easily combined with usual care. Because of the positive predictive value of 73.5%, it remains necessary to confirm AF with a 12 lead ECG or 24-h Holter monitoring.
确定老年患者反复筛查心房颤动(AF)的诊断率。
一项实用的前瞻性队列研究,对老年队列应用手持式单导联心电图设备(SLD)进行AF机会性筛查。65岁及以上连续就诊于老年门诊的患者符合纳入条件。先进行12导联心电图检查,随后在每次老年门诊就诊时使用SLD进行测量。衰弱指数基于缺陷累积模型。
478例患者符合条件。若患者未签署知情同意书(17例)、有起搏器或植入式心律转复除颤器(20例)或医疗文件不完整(2例),则被排除。排除后,439例患者参与本研究。平均年龄为78岁(范围65至100岁),54%为女性。89例患者(20%)已知患有AF,4例患者(1%)在基线心电图上首次检测到AF,20例患者(5%)在随访期间首次通过SLD检测到AF。SLD的敏感性为90.0%,特异性为99.0%,阴性预测值为99.7%,阳性预测值为73.5%。大多数AF患者(82%)虚弱,53%严重虚弱。
老年患者反复筛查的诊断率比常规护理高五倍。它很容易与常规护理相结合。由于阳性预测值为73.5%,仍有必要通过12导联心电图或24小时动态心电图监测来确诊AF。