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免疫暴露的结构化模型。

A structured model for immune exposures.

机构信息

Division for Vaccine Discovery, 9420 Athena Circle La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

Knocean Inc., 2 - 107 Quebec Ave Toronto M6P 2T3, Ontario, Canada.

出版信息

Database (Oxford). 2020 Jan 1;2020. doi: 10.1093/database/baaa016.

Abstract

An Immune Exposure is the process by which components of the immune system first encounter a potential trigger. The ability to describe consistently the details of the Immune Exposure process was needed for data resources responsible for housing scientific data related to the immune response. This need was met through the development of a structured model for Immune Exposures. This model was created during curation of the immunology literature, resulting in a robust model capable of meeting the requirements of such data. We present this model with the hope that overlapping projects will adopt and or contribute to this work.

摘要

免疫暴露是免疫系统的各个组成部分首次接触潜在触发因素的过程。需要有一种能够一致地描述免疫暴露过程细节的方法,以便为负责存储与免疫反应相关科学数据的数据源提供支持。这一需求通过开发免疫暴露的结构化模型得到了满足。该模型是在对免疫学文献进行策展的过程中创建的,因此它是一个功能强大的模型,能够满足这些数据的要求。我们提出这个模型,希望重叠的项目能够采用并为此项工作做出贡献。

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A structured model for immune exposures.免疫暴露的结构化模型。
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The Immune Epitope Database (IEDB): 2018 update.免疫表位数据库(IEDB):2018 年更新。
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