IEEE J Biomed Health Inform. 2020 Sep;24(9):2461-2472. doi: 10.1109/JBHI.2020.2981526. Epub 2020 Apr 13.
Automated electrocardiogram (ECG) analysis for arrhythmia detection plays a critical role in early prevention and diagnosis of cardiovascular diseases. Extracting powerful features from raw ECG signals for fine-grained diseases classification is still a challenging problem today due to variable abnormal rhythms and noise distribution. For ECG analysis, the previous research works depend mostly on heartbeat or single scale signal segments, which ignores underlying complementary information of different scales. In this paper, we formulate a novel end-to-end Deep Multi-Scale Fusion convolutional neural network (DMSFNet) architecture for multi-class arrhythmia detection. Our proposed approach can effectively capture abnormal patterns of diseases and suppress noise interference by multi-scale feature extraction and cross-scale information complementarity of ECG signals. The proposed method implements feature extraction for signal segments with different sizes by integrating multiple convolution kernels with different receptive fields. Meanwhile, joint optimization strategy with multiple losses of different scales is designed, which not only learns scale-specific features, but also realizes cumulatively multi-scale complementary feature learning during the learning process. In our work, we demonstrate our DMSFNet on two open datasets (CPSC_2018 and PhysioNet/CinC_2017) and deliver the state-of-art performance on them. Among them, CPSC_2018 is a 12-lead ECG dataset and CinC_2017 is a single-lead dataset. For these two datasets, we achieve the F1 score [Formula: see text] and [Formula: see text] which are higher than previous state-of-art approaches respectively. The results demonstrate that our end-to-end DMSFNet has outstanding performance for feature extraction from a broad range of distinct arrhythmias and elegant generalization ability for effectively handling ECG signals with different leads.
自动心电图 (ECG) 分析在心律失常检测中起着至关重要的作用,有助于心血管疾病的早期预防和诊断。由于异常节律和噪声分布的多变性,从原始 ECG 信号中提取用于细粒度疾病分类的强大特征仍然是一个具有挑战性的问题。在 ECG 分析中,以前的研究工作主要依赖于心跳或单一尺度的信号段,而忽略了不同尺度下的潜在互补信息。在本文中,我们提出了一种新颖的端到端深度多尺度融合卷积神经网络 (DMSFNet) 架构,用于多类心律失常检测。我们的方法可以通过多尺度特征提取和 ECG 信号的跨尺度信息互补,有效地捕捉疾病的异常模式并抑制噪声干扰。该方法通过整合具有不同感受野的多个卷积核,对不同大小的信号段进行特征提取。同时,设计了具有多个不同尺度损失的联合优化策略,不仅可以学习尺度特定的特征,而且可以在学习过程中实现累积多尺度互补特征学习。在我们的工作中,我们在两个公开数据集 (CPSC_2018 和 PhysioNet/CinC_2017) 上验证了我们的 DMSFNet,并在这两个数据集上取得了最先进的性能。其中,CPSC_2018 是一个 12 导联 ECG 数据集,CinC_2017 是一个单导联数据集。对于这两个数据集,我们分别实现了 [Formula: see text] 和 [Formula: see text] 的 F1 分数,优于之前的最先进方法。结果表明,我们的端到端 DMSFNet 具有从广泛的不同心律失常中提取特征的出色性能,并且具有优雅的泛化能力,可有效处理不同导联的 ECG 信号。