Yunnan University of Traditional Chinese Medicine, Kunming, P. R. China.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. China.
Nat Prod Res. 2021 Nov;35(21):3901-3907. doi: 10.1080/14786419.2020.1749609. Epub 2020 Apr 14.
Three new diterpenoids () (two abietane type diterpenoids and a paralianone type diterpenoid), together with four known compounds () were isolated from the whole plants of . Their structures were elucidated through spectroscopic analysis and physicochemical characteristics. The cytotoxic activities of compounds against five human tumour cell lines were evaluated, however, they were inactive at the concentration of 40 μM. The compound enhanced lysosomal biogenesis with Lyso Tracker staining intensity of 132.6%.
从 全株植物中分离得到三个新的二萜（）（两个松香烷型二萜和一个偏诺烷型二萜）和四个已知化合物（）。通过光谱分析和理化特性阐明了它们的结构。对化合物 对五种人肿瘤细胞系的细胞毒性活性进行了评价，但在 40μM 浓度时没有活性。化合物 增强了溶酶体生物发生，用 Lyso Tracker 染色强度为 132.6%。
