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养老院居民髋部骨折发病率的长期变化趋势。

Secular Trends in the Incidence of Hip Fracture Among Nursing Home Residents.

机构信息

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Hinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Boston, MA, USA.

出版信息

J Bone Miner Res. 2020 Sep;35(9):1668-1675. doi: 10.1002/jbmr.4032. Epub 2020 May 8.

Abstract

A recent study suggested a decline in the incidence of hip fracture among US women between 2002 and 2012, followed by a leveling in the incidence rate from 2013 to 2015. Newly admitted nursing home residents are particularly vulnerable to hip fracture, and it is unclear whether that trend is observed in this high risk group. The purpose of our study was to describe trends in hip fracture rates and postfracture mortality among 2.6 million newly admitted US nursing home residents from 2007 to 2015, and to examine whether these trends could be explained by differences in resident characteristics. Medicare claims data were linked with the Minimum Data Set (MDS), a clinical assessment performed quarterly on all nursing home residents. In each year (2007-2015), we identified newly admitted long-stay (ie, 100 days in the same facility) nursing home residents. Hip fracture was defined using Medicare Part A diagnostic codes. Follow-up time was calculated from the index date until the first event of hospitalized hip fracture, Medicare disenrollment, death, or until 1 year. Poisson regression was used to adjust rates of hip fracture for age and sex. The number of newly admitted nursing home residents ranged from 324,508 in 2007 to 257,350 in 2015. Although mean age remained similar (83 years), residents were more functionally dependent over time. There was a small absolute decrease in the incidence rate of hip fracture between 2007 (3.32/100 person-years) and 2013 (2.82/100 person-years), with an increase again in 2015 (3.03/100 person-years). Adjusting for patient characteristics somewhat attenuated these trends. One-year mortality was high following fracture in all years (42.6% in 2007, 42.1% in 2014). In summary, we observed a recent slight rise in the incidence rates of hip fracture among nursing home residents that was at least partially explained by differences in resident characteristics over time. © 2020 American Society for Bone and Mineral Research.

摘要

最近的一项研究表明,2002 年至 2012 年间,美国女性髋部骨折的发病率有所下降,2013 年至 2015 年期间发病率持平。新入住养老院的居民特别容易发生髋部骨折,目前尚不清楚这一趋势是否在这一高风险人群中出现。我们的研究目的是描述 2007 年至 2015 年间 260 万新入住美国养老院居民的髋部骨折发生率和骨折后死亡率趋势,并探讨这些趋势是否可以用居民特征的差异来解释。医疗保险索赔数据与最小数据集(MDS)相关联,MDS 是对所有养老院居民每季度进行的一次临床评估。在每一年(2007-2015 年),我们确定了新入住的长期(即在同一机构居住 100 天)养老院居民。髋部骨折使用医疗保险 A 部分诊断代码定义。随访时间从索引日期计算至首次住院髋部骨折、医疗保险退保、死亡或 1 年。泊松回归用于调整髋部骨折发生率的年龄和性别。新入住养老院的居民人数从 2007 年的 324508 人减少到 2015 年的 257350 人。尽管平均年龄保持相似(83 岁),但居民的功能依赖性随着时间的推移逐渐增强。2007 年(3.32/100 人年)和 2013 年(2.82/100 人年)之间髋部骨折发生率略有绝对下降,2015 年再次上升(3.03/100 人年)。根据患者特征进行调整后,这些趋势有所减弱。所有年份骨折后 1 年死亡率均较高(2007 年为 42.6%,2014 年为 42.1%)。总之,我们观察到养老院居民髋部骨折的发病率最近略有上升,这至少部分可以用居民特征随时间的变化来解释。

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