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Intracavernous injection of vasoactive drugs in the rabbit.

作者信息

Stackl W, Loupal G, Holzmann A

机构信息

Department of Urology, University of Vienna, Veterinary School, Austria.

出版信息

Urol Res. 1988;16(6):455-8. doi: 10.1007/BF00280029.

DOI:10.1007/BF00280029
PMID:3232278
Abstract

To investigate the erectile response and side effects of intracavernous injection of vasoactive agents, 7 groups of 5 rabbits each underwent injection of either isotonic saline or 1 of 6 drugs. Phentolamine most consistently produced full erection with few inflammatory reactions, while phenoxybenzamine produced erection but also severe inflammation and sclerosis of the corpus cavernosum. With prostaglandin E1, neither erection nor inflammation was observed.

摘要

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引用本文的文献

1
The rabbit as an intracavernous injection study model.兔子作为海绵体内注射研究模型。
Urol Res. 1996;24(1):27-32. doi: 10.1007/BF00296730.
2
Intracavernous prostaglandin E1 in erectile dysfunction.阴茎海绵体内注射前列腺素E1治疗勃起功能障碍
Clin Investig. 1994 Jan;72(2):139-49. doi: 10.1007/BF00184593.

本文引用的文献

1
Cavernosal alpha-blockade: a warning.海绵体α-阻滞剂:一则警示。
Br J Psychiatry. 1984 Mar;144:329-30. doi: 10.1192/bjp.144.3.329b.
2
Intracavernous injection of papaverine as a diagnostic and therapeutic method in erectile failure.
Angiology. 1984 Feb;35(2):79-87. doi: 10.1177/000331978403500203.
3
Contraction and relaxation induced by some prostanoids in isolated human penile erectile tissue and cavernous artery.一些前列腺素在离体人阴茎勃起组织和海绵体动脉中诱导的收缩和舒张。
J Urol. 1985 Dec;134(6):1245-50. doi: 10.1016/s0022-5347(17)47704-4.
4
Pilot experiments on the actions of drugs injected into the human corpus cavernosum penis.关于注入人体阴茎海绵体内的药物作用的初步实验。
Br J Pharmacol. 1986 Mar;87(3):495-500. doi: 10.1111/j.1476-5381.1986.tb10191.x.
5
Chronic papaverine treatment: the effect of repeated injections on the simian erectile response and penile tissue.慢性罂粟碱治疗:重复注射对猿猴勃起反应及阴茎组织的影响。
J Urol. 1987 Nov;138(5):1263-6. doi: 10.1016/s0022-5347(17)43581-6.
6
Diagnostic intracorporeal papaverine and erectile dysfunction.诊断性体内注射罂粟碱与勃起功能障碍
Br J Urol. 1987 Mar;59(3):264-6. doi: 10.1111/j.1464-410x.1987.tb04620.x.
7
Physiology of erection and pharmacological management of impotence.
J Urol. 1987 May;137(5):829-36. doi: 10.1016/s0022-5347(17)44267-4.
8
Intracavernous injection of prostaglandin E1 in impotent men.
J Urol. 1988 Jul;140(1):66-8. doi: 10.1016/s0022-5347(17)41488-1.
9
Effect of local alpha-adrenergic blockade on human penile erection.局部α-肾上腺素能阻滞对人类阴茎勃起的影响。
J Urol. 1985 Sep;134(3):479-81. doi: 10.1016/s0022-5347(17)47248-x.
10
Auto-injection of the corpus cavernosum with a vasoactive drug combination for vasculogenic impotence.
J Urol. 1985 Jan;133(1):39-41. doi: 10.1016/s0022-5347(17)48774-x.