Malbert C H, Pangui L J, Dorchies P, Ruckebusch Y
INRA, Laboratoire associé de Physiologie, Ecole Nationale Vétérinaire, Toulouse, France.
Ann Rech Vet. 1988;19(4):237-43.
Transmural potential difference, pH and ionic concentrations of the abomasal contents were measured in three calves. Antroduodenal motor patterns were recorded using electrodes and strain-gauge transducers fixed on the antrum and the duodenum. The calves were infected with 8 x 10(9) Babesia major intravenously and a significant drop in transmural potential difference, concomitant with a steady increase in Na+ and K+ concentrations of the abomasal contents occurred within 2 days. The onset of fever on the 5th day after infection was associated with an increased frequency of duodenal migrating myoelectric complexes and episodes of bradygastria on the distal antrum. These changes disappeared at the end of fever. We conclude that transmural potential difference changes and Na+-K+ concentrations in the abomasal fluid could reflect changes in the ionic permeability of the gastric wall. These effects may represent early signs of Babesia infection.
在三头犊牛中测量了皱胃内容物的跨壁电位差、pH值和离子浓度。使用固定在胃窦和十二指肠上的电极和应变片式传感器记录胃十二指肠运动模式。给犊牛静脉注射8×10⁹个大型巴贝斯虫，在2天内跨壁电位差显著下降，同时皱胃内容物中Na⁺和K⁺浓度稳步增加。感染后第5天发热的开始与十二指肠移行性肌电复合波频率增加以及远端胃窦的胃动过缓发作有关。这些变化在发热结束时消失。我们得出结论，皱胃液中的跨壁电位差变化和Na⁺-K⁺浓度可反映胃壁离子通透性的变化。这些效应可能代表巴贝斯虫感染的早期迹象。
