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吸烟对 IgE、氧化应激和血红蛋白浓度的影响。

The Effects of Smoking on IgE, Oxidative Stress and Haemoglobin Concentration.

机构信息

Department of Medical Laboratory Technology, Health-Technical College, Erbil Polytechnic University, Erbil, Kurdistan Region, Iraq.

Department of Hematology, Hiwa Cancer Hospital, Sulaymaniyah, Kurdistan Region, Iraq.

出版信息

Asian Pac J Cancer Prev. 2020 Apr 1;21(4):1069-1072. doi: 10.31557/APJCP.2020.21.4.1069.

Abstract

BACKGROUND

Smoking is a well-known related factor for many health problems in a human being through different ways of exposure.

OBJECTIVES

Thie aim of the study was to examine the effects of different types of cigarette smoking on hemoglobin level, high sensitive C-Reactive Protein (hsCRP), Malondialdehyde (MDA), and IgE levels in healthy adult subjects.

METHODS

One hundred seventy-one healthy adult females and males were included in this study. They divided into four groups: cigarette, shisha, passive smokers, and non-smokers groups. Serum samples from all groups analyzed for hemoglobin, hsCRP, IgE, and malondialdehyde level.

RESULTS

The mean MDA, IgE, and hemoglobin levels significantly increased in both smokers (cigarette and Shisha groups) and passive smokers than in non-smokers group (p<0.05). The hsCRP levels were significantly increased (p<0.05) in cigarette and Shisha smokers compared to non-smokers. At the same time, there was a non-significant relationship between passive smoker in comparison to non-smokers (p>0.05).

CONCLUSION

This study concluded that smoking, including cigarette and shisha, even passive smoking harmed health through increasing Malondialdehyde, serum IgE and hs-CRP levels in the body.

摘要

背景

吸烟通过不同的暴露途径是许多人类健康问题的已知相关因素。

目的

本研究旨在检查不同类型的吸烟对健康成年受试者的血红蛋白水平、高敏 C 反应蛋白 (hsCRP)、丙二醛 (MDA)和 IgE 水平的影响。

方法

本研究纳入了 171 名健康成年女性和男性。他们被分为四组:香烟组、水烟组、被动吸烟者组和不吸烟者组。分析所有组的血清样本中的血红蛋白、hsCRP、IgE 和 MDA 水平。

结果

与不吸烟者相比,吸烟者(香烟和水烟组)和被动吸烟者的 MDA、IgE 和血红蛋白水平均显著升高(p<0.05)。与不吸烟者相比,香烟和水烟吸烟者的 hsCRP 水平显著升高(p<0.05)。同时,与不吸烟者相比,被动吸烟者的水平无显著差异(p>0.05)。

结论

本研究表明,吸烟,包括香烟和水烟,甚至被动吸烟都会通过增加体内丙二醛、血清 IgE 和 hs-CRP 水平来损害健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ad/7445955/bc7ecea0aab6/APJCP-21-1069-g001.jpg

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