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持续努力研究纳米材料的环境健康与安全对于维持纳米产业的可持续增长至关重要。

Continued Efforts on Nanomaterial-Environmental Health and Safety Is Critical to Maintain Sustainable Growth of Nanoindustry.

机构信息

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.

College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.

出版信息

Small. 2020 May;16(21):e2000603. doi: 10.1002/smll.202000603. Epub 2020 Apr 27.

Abstract

Nanotechnology is enjoying an impressive growth and the global nanotechnology industry is expected to exceed US$ 125 billion by 2024. Based on these successes, there are notions that enough is known and efforts on engineered nanomaterial environmental health and safety (nano-EHS) research should be put on the back burner. However, there are recent events showing that it is not the case. The US Food and Drug Administration found ferumoxytol (carbohydrate-coated superparamagnetic iron oxide nanoparticle) for anemia treatment could induce lethal anaphylactic reactions. The European Union will categorize TiO as a category 2 carcinogen due to its inhalation hazard and France banned use of TiO (E171) in food from January 1, 2020 because of its carcinogenic potential. Although nanoindustry is seemingly in a healthy state, growth could be hindered for the lack of certainty and more nano-EHS research is needed for the sustainable growth of nanoindustry. Herein, the current knowledge gaps and the way forward are elaborated.

摘要

纳米技术正在蓬勃发展,预计到 2024 年,全球纳米技术产业将超过 1250 亿美元。基于这些成功,有人认为已经了解了足够多的知识,应该将工程纳米材料环境健康与安全(nano-EHS)研究的工作放在次要位置。然而,最近发生的一些事件表明事实并非如此。美国食品和药物管理局发现,用于治疗贫血的 Ferumoxytol(碳水化合物涂层超顺磁性氧化铁纳米颗粒)可能会引发致命的过敏性反应。由于吸入危害,欧盟将 TiO 归类为 2 类致癌物,法国还因为其致癌潜力,从 2020 年 1 月 1 日起禁止在食品中使用 TiO(E171)。尽管纳米产业看似处于健康状态,但由于缺乏确定性,其增长可能会受到阻碍,因此需要进行更多的 nano-EHS 研究,以实现纳米产业的可持续增长。本文详细阐述了当前的知识空白和未来的发展方向。

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