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儿童和青少年单次创伤后 ICD-11 创伤后应激障碍和复杂创伤后应激障碍诊断的患病率和预测价值。

Prevalence and predictive value of ICD-11 post-traumatic stress disorder and Complex PTSD diagnoses in children and adolescents exposed to a single-event trauma.

机构信息

MRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.

Centre for Emotional Health, Macquarie University, Sydney, NSW, Australia.

出版信息

J Child Psychol Psychiatry. 2021 Mar;62(3):270-276. doi: 10.1111/jcpp.13240. Epub 2020 Apr 28.

Abstract

BACKGROUND

The 11th edition of the International Classification of Diseases (ICD-11) made a number of significant changes to the diagnostic criteria for post-traumatic stress disorder (PTSD). We sought to determine the prevalence and 3-month predictive values of the new ICD-11 PTSD criteria relative to ICD-10 PTSD, in children and adolescents following a single traumatic event. ICD-11 also introduced a diagnosis of Complex PTSD (CPTSD), proposed to typically result from prolonged, chronic exposure to traumatic experiences, although the CPTSD diagnostic criteria do not require a repeated experience of trauma. We therefore explored whether children and adolescents demonstrate ICD-11 CPTSD features following exposure to a single-incident trauma.

METHOD

Data were analysed from a prospective cohort study of youth aged 8-17 years who had attended an emergency department following a single trauma. Assessments of PTSD, CPTSD, depressive and anxiety symptoms were performed at two to four weeks (n = 226) and nine weeks (n = 208) post-trauma, allowing us to calculate and compare the prevalence and predictive value of ICD-10 and ICD-11 PTSD criteria, along with CPTSD. Predictive abilities of different diagnostic thresholds were undertaken using positive/negative predictive values, sensitivity/specificity statistics and logistic regressions.

RESULTS

At Week 9, 15 participants (7%) were identified as experiencing ICD-11 PTSD, compared to 23 (11%) experiencing ICD-10 PTSD. There was no significant difference in comorbidity rates between ICD-10 and ICD-11 PTSD diagnoses. Ninety per cent of participants with ICD-11 PTSD also met criteria for at least one CPTSD feature. Five participants met full CPTSD criteria.

CONCLUSIONS

Reduced prevalence of PTSD associated with the use of ICD-11 criteria is likely to reduce identification of PTSD relative to using ICD-10 criteria but not relative to DSM-4 and DSM-5 criteria. Diagnosis of CPTSD is likely to be infrequent following single-incident trauma.

摘要

背景

国际疾病分类第 11 版(ICD-11)对创伤后应激障碍(PTSD)的诊断标准进行了多项重大修改。我们旨在确定相对于 ICD-10 PTSD,新的 ICD-11 PTSD 标准在经历单一创伤事件后,在儿童和青少年中的患病率和 3 个月预测值。ICD-11 还引入了复杂创伤后应激障碍(CPTSD)的诊断,据推测,CPTSD 通常是由于长期、慢性暴露于创伤性经历所致,尽管 CPTSD 的诊断标准并不要求重复经历创伤。因此,我们探讨了儿童和青少年在经历单一创伤事件后是否表现出 ICD-11 CPTSD 特征。

方法

对 226 名年龄在 8-17 岁之间的青年进行前瞻性队列研究,这些青年在经历单一创伤后到急诊室就诊。在创伤后 2-4 周(n=226)和 9 周(n=208)进行 PTSD、CPTSD、抑郁和焦虑症状评估,使我们能够计算和比较 ICD-10 和 ICD-11 PTSD 标准以及 CPTSD 的患病率和预测值。使用阳性/阴性预测值、敏感性/特异性统计和逻辑回归来评估不同诊断阈值的预测能力。

结果

在第 9 周,有 15 名参与者(7%)被诊断为患有 ICD-11 PTSD,而 23 名参与者(11%)被诊断为患有 ICD-10 PTSD。ICD-10 和 ICD-11 PTSD 诊断的共病率没有显著差异。90%的 ICD-11 PTSD 患者也符合至少一个 CPTSD 特征的标准。有 5 名参与者符合完整的 CPTSD 标准。

结论

与使用 ICD-10 标准相比,使用 ICD-11 标准导致 PTSD 的患病率降低,这可能会降低 PTSD 的识别率,但与 DSM-4 和 DSM-5 标准相比则不会。在经历单一创伤事件后,CPTSD 的诊断可能不太常见。

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