• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

荧光染料在内镜检查和诊断研究中的应用。

Use of Fluorescent Dyes in Endoscopy and Diagnostic Investigation.

作者信息

Hoffman Arthur, Atreya Raja, Rath Timo, Neurath Markus F

机构信息

Department of Internal Medicine III, Clinic Aschaffenburg-Alzenau, Aschaffenburg, Germany.

First Department of Medicine, Friedrich Alexander University Erlangen-Nuernberg, Erlangen, Germany.

出版信息

Visc Med. 2020 Apr;36(2):95-103. doi: 10.1159/000506241. Epub 2020 Mar 24.

DOI:10.1159/000506241
PMID:32355666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7184845/
Abstract

BACKGROUND

The advancement of innovative endoscopic technology in terms of improving the visualization of the mucosa has been of significant benefit.

SUMMARY

Advancements in image resolution, software processing, and optical filter technology have resulted in several techniques complemental to traditional white light endoscopy. These new techniques provide a real-time optical diagnosis as well as virtual histology of detected lesions. Optical molecular imaging permits a functional assessment within cells.

KEY MESSAGE

Optical molecular imaging provides an understanding of cellular processes and permits validation of the specificity of fluorescent tracers and the possibility of quantifying the signal.

摘要

背景

创新内镜技术在改善黏膜可视化方面取得的进展具有重大意义。

总结

图像分辨率、软件处理和光学滤光技术的进步催生了多种补充传统白光内镜检查的技术。这些新技术可提供实时光学诊断以及对检测到的病变进行虚拟组织学分析。光学分子成像能够对细胞内进行功能评估。

关键信息

光学分子成像有助于理解细胞过程,并能验证荧光示踪剂的特异性以及对信号进行量化的可能性。

相似文献

1
Use of Fluorescent Dyes in Endoscopy and Diagnostic Investigation.荧光染料在内镜检查和诊断研究中的应用。
Visc Med. 2020 Apr;36(2):95-103. doi: 10.1159/000506241. Epub 2020 Mar 24.
2
Advanced endoscopic imaging: a review of commercially available technologies.高级内镜成像:商业上可用技术的综述。
Clin Gastroenterol Hepatol. 2014 Mar;12(3):368-76.e1. doi: 10.1016/j.cgh.2013.06.015. Epub 2013 Jun 28.
3
Advances in the Endoscopic Assessment of Inflammatory Bowel Diseases: Cooperation between Endoscopic and Pathologic Evaluations.炎症性肠病内镜评估的进展:内镜与病理评估之间的合作
J Pathol Transl Med. 2015 May;49(3):209-17. doi: 10.4132/jptm.2015.04.09. Epub 2015 May 15.
4
Confocal laser endomicroscopy and narrow-band imaging-aided endoscopy for in vivo imaging of colitis and colon cancer in mice.共聚焦激光内窥显微镜和窄带成像辅助内镜在活体成像小鼠结肠炎和结肠癌中的应用。
Nat Protoc. 2011 Sep 1;6(9):1471-81. doi: 10.1038/nprot.2011.377.
5
High technology imaging in digestive endoscopy.消化内镜检查中的高科技成像
World J Gastrointest Endosc. 2012 Feb 16;4(2):22-7. doi: 10.4253/wjge.v4.i2.22.
6
[Endoscopic imaging techniques in the diagnosis of laryngeal carcinoma and its precursor lesions].[内镜成像技术在喉癌及其癌前病变诊断中的应用]
Laryngorhinootologie. 1999 Dec;78(12):685-91. doi: 10.1055/s-1999-8775.
7
Endoscopic Diagnosis for H. pylori Infection: White Light Imaging (WLI) vs. Image-Enhanced Endoscopy (IEE).幽门螺杆菌感染的内镜诊断:白光成像(WLI)与影像增强内镜(IEE)。
Asian Pac J Cancer Prev. 2021 Sep 1;22(9):3031-3038. doi: 10.31557/APJCP.2021.22.9.3031.
8
Diagnostic Value of Narrow Band Imaging in Visualization of Pathological Lesions in Larynx and Hypopharynx.窄带成像在喉和下咽病理病变可视化中的诊断价值。
Acta Medica (Hradec Kralove). 2021;64(1):22-28. doi: 10.14712/18059694.2021.4.
9
Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study.使用共聚焦微内镜和适用染料对头颈部鳞状细胞癌进行实时成像:初步研究。
Auris Nasus Larynx. 2020 Aug;47(4):668-675. doi: 10.1016/j.anl.2020.02.001. Epub 2020 Feb 20.
10
Computed virtual chromoendoscopy: a new tool for enhancing tissue surface structures.计算机虚拟染色内镜检查:一种增强组织表面结构的新工具。
Endoscopy. 2007 Jan;39(1):80-3. doi: 10.1055/s-2006-945045.

引用本文的文献

1
Wide field-of-view fluorescence imaging for organ-level lineage tracing of rare intestinal stem cell populations.宽视场荧光成像用于稀有肠干细胞群体的器官水平谱系追踪。
J Biomed Opt. 2023 Sep;28(9):096004. doi: 10.1117/1.JBO.28.9.096004. Epub 2023 Sep 13.
2
Phthalocyanine-Blue Nanoparticles for the Direct Visualization of Tumors with White Light Illumination.酞菁蓝纳米粒子可用于在白光照射下直接可视化肿瘤。
ACS Appl Mater Interfaces. 2023 Jul 19;15(28):33373-33381. doi: 10.1021/acsami.3c05140. Epub 2023 Jul 3.
3
Robotics in Surgery and Endoscopy.手术与内窥镜检查中的机器人技术。
Visc Med. 2020 Apr;36(2):69. doi: 10.1159/000506657. Epub 2020 Mar 17.

本文引用的文献

1
Quantitative fluorescence endoscopy: an innovative endoscopy approach to evaluate neoadjuvant treatment response in locally advanced rectal cancer.定量荧光内镜检查:一种评估局部晚期直肠癌新辅助治疗反应的创新内镜检查方法。
Gut. 2020 Mar;69(3):406-410. doi: 10.1136/gutjnl-2019-319755. Epub 2019 Sep 18.
2
Emerging optical methods for endoscopic surveillance of Barrett's oesophagus.新兴的光学方法用于 Barrett 食管的内镜监测。
Lancet Gastroenterol Hepatol. 2018 May;3(5):349-362. doi: 10.1016/S2468-1253(18)30030-X. Epub 2018 Apr 6.
3
Molecular endoscopy for targeted imaging in the digestive tract.分子内窥镜用于消化道的靶向成像。
Lancet Gastroenterol Hepatol. 2016 Oct;1(2):147-155. doi: 10.1016/S2468-1253(16)30027-9. Epub 2016 Sep 8.
4
Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn's disease.使用荧光抗粘附抗体维多珠单抗对克罗恩病黏膜α4β7整合素表达进行分子成像。
Gastrointest Endosc. 2017 Aug;86(2):406-408. doi: 10.1016/j.gie.2017.01.012. Epub 2017 Jan 27.
5
Hyperspectral imaging fluorescence excitation scanning for colon cancer detection.用于结肠癌检测的高光谱成像荧光激发扫描
J Biomed Opt. 2016 Oct 1;21(10):104003. doi: 10.1117/1.JBO.21.10.104003.
6
Integrated Endoscopic System Based on Optical Imaging and Hyperspectral Data Analysis for Colorectal Cancer Detection.基于光学成像和高光谱数据分析的集成式内窥镜系统用于结直肠癌检测
Anticancer Res. 2016 Aug;36(8):3925-32.
7
Snapshot hyperspectral retinal imaging using compact spectral resolving detector array.使用紧凑型光谱分辨探测器阵列的快照高光谱视网膜成像。
J Biophotonics. 2017 Jun;10(6-7):830-839. doi: 10.1002/jbio.201600053. Epub 2016 Jul 19.
8
Predicting Therapeutic Response by in vivo Molecular Imaging in Inflammatory Bowel Diseases.通过体内分子成像预测炎症性肠病的治疗反应
Dig Dis. 2016;34(5):552-7. doi: 10.1159/000445262. Epub 2016 Jun 22.
9
In vivo oximetry of human bulbar conjunctival and episcleral microvasculature using snapshot multispectral imaging.使用快照多光谱成像技术对人球结膜和巩膜上微血管进行体内血氧测定。
Exp Eye Res. 2016 Aug;149:48-58. doi: 10.1016/j.exer.2016.06.008. Epub 2016 Jun 15.
10
Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection.多光谱荧光成像在人卵巢和输卵管组织早期癌症检测中的应用。
J Biomed Opt. 2016 May 1;21(5):56005. doi: 10.1117/1.JBO.21.5.056005.