Hoffman Arthur, Atreya Raja, Rath Timo, Neurath Markus F
Department of Internal Medicine III, Clinic Aschaffenburg-Alzenau, Aschaffenburg, Germany.
First Department of Medicine, Friedrich Alexander University Erlangen-Nuernberg, Erlangen, Germany.
Visc Med. 2020 Apr;36(2):95-103. doi: 10.1159/000506241. Epub 2020 Mar 24.
The advancement of innovative endoscopic technology in terms of improving the visualization of the mucosa has been of significant benefit.
Advancements in image resolution, software processing, and optical filter technology have resulted in several techniques complemental to traditional white light endoscopy. These new techniques provide a real-time optical diagnosis as well as virtual histology of detected lesions. Optical molecular imaging permits a functional assessment within cells.
Optical molecular imaging provides an understanding of cellular processes and permits validation of the specificity of fluorescent tracers and the possibility of quantifying the signal.
创新内镜技术在改善黏膜可视化方面取得的进展具有重大意义。
图像分辨率、软件处理和光学滤光技术的进步催生了多种补充传统白光内镜检查的技术。这些新技术可提供实时光学诊断以及对检测到的病变进行虚拟组织学分析。光学分子成像能够对细胞内进行功能评估。
光学分子成像有助于理解细胞过程,并能验证荧光示踪剂的特异性以及对信号进行量化的可能性。