新型冠状病毒肺炎患者眼表中的严重急性呼吸综合征冠状病毒2
SARS-CoV-2 in the ocular surface of COVID-19 patients.
作者信息
Xie Hua-Tao, Jiang Shi-Yun, Xu Kang-Kang, Liu Xin, Xu Bing, Wang Lin, Zhang Ming-Chang
机构信息
1Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022 China.
2Department of Clinical Laboratory, Research Center for Tissue Engineering and Regenerative Medicine, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022 China.
出版信息
Eye Vis (Lond). 2020 Apr 26;7:23. doi: 10.1186/s40662-020-00189-0. eCollection 2020.
Abstract
The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.
摘要
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019新型冠状病毒病（COVID-19）已在全球范围内传播，而该病毒的传播途径仍存在争议。我们招募了33例无任何眼部表现的患者，采集其眼表拭子进行病毒检测。在两名患者的双眼样本中均检测到RNA呈强阳性。因此，SARS-CoV-2可能存在于COVID-19患者的正常眼表，提示该病毒可能通过结膜接触传播。
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