Wang Min, Guo Linghong, Chen Qi, Xia Guojin, Wang Bo
Department of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
Aging (Albany NY). 2020 May 2;12(9):7652-7659. doi: 10.18632/aging.103170.
We aimed to describe typical radiological features and progression of Coronavirus disease 2019 (COVID-19) patients. We reviewed the chest CT scans, laboratory findings, and clinical records of 66 COVID-19 patients who were admitted to affiliated hospitals of Nanchang university, Nanchang, China, from Jan 21 to Feb 2, 2020. CT was used to evaluate the radiological characteristics of COVID-19 patients. Only 4 patients (4/66, 6%) claimed their exposure to COVID-19 pneumonia patients. The major symptoms were fever (60/66, 91%) and cough (37/66, 56%). The predominant features of lesion were scattered (43/66, 65%), bilateral (50/66, 76%), ground-glass opacity (64/66, 97%), and air bronchogram sign (47/66, 71%). Forty-eight patients (48/66, 73%) had more than two lobes involved. Right lower lobe (58/66, 88%) and left lower lobe (49/66, 74%) were most likely invaded. Twelve patients (12/66, 18%) had at least one comorbid condition. Pleural traction (29/66, 44%), crazy paving (15/66, 23%), interlobular septal thickening (11/66, 17%), and consolidation (7/66, 11%) were also observed. The typical radiology features of COVID-19 patients are scattered ground-glass opacity in the bilateral lobes. Fever and cough are the major symptoms. Evaluating chest CT, clinical symptoms, and laboratory results could facilitate the early diagnosis of COVID-19, and judge disease progression.
我们旨在描述2019年冠状病毒病（COVID-19）患者的典型影像学特征及病情进展。我们回顾了2020年1月21日至2月2日在中国南昌的南昌大学附属医院收治的66例COVID-19患者的胸部CT扫描结果、实验室检查结果及临床记录。CT用于评估COVID-19患者的影像学特征。仅有4例患者（4/66，6%）称接触过COVID-19肺炎患者。主要症状为发热（60/66，91%）和咳嗽（37/66，56%）。病变的主要特征为散在分布（43/
66，65%）、双侧受累（50/66，76%）、磨玻璃影（64/66，97%）及空气支气管征（47/66，71%）。48例患者（48/66，73%）累及两个以上肺叶。右下叶（58/66，88%）和左下叶（49/66，74%）最易受累。1
2例患者（12/66，18%）至少有一种合并症。还观察到胸膜牵拉（29/66，44%）、铺路石征（15/66，23%）、小叶间隔增厚（11/66，17%）及实变（7/66，11%）。COVID-19患者的典型影像学特征为双侧肺叶散在磨玻璃影。发热和咳嗽是主要症状。评估胸部CT、临床症状及实验室检查结果有助于COVID-19的早期诊断及判断病情进展。
