Asmilia Nuzul, Fahrimal Yudha, Abrar Mahdi, Rinidar Rinidar
Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
Clinical Laboratory, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
ScientificWorldJournal. 2020 Apr 27;2020:2739056. doi: 10.1155/2020/2739056. eCollection 2020.
Malacca () is one of the plants that is often by the community in the Aceh Besar district of Indonesia as a traditional medicine for the treatment of various diseases such as antimicrobial, antibacterial, antifungals, antivirals, antimutagenic, antimalaria, and antiallergic. This research was conducted to analyze the content of chemical compounds in the ethanol extract of the Malacca leaf (EEDM) using a gas chromatography-mass spectrophotometer (GC-MS). Malacca leaves were extracted by the maceration method using n-hexane, ethyl acetate, and ethanol. The GC-MS analysis showed EEDM contained 22 chemical compounds. The highest chemical content of EEDM is octadecanoic acid reaching 22.93%, 9,12-octadecanoic acid 14.99%, octadecanoic acid 7.59%, 9-hexadecenoic acid 6.17%, octadecanoic acid 5.95%, octadecanal 5.59%, 9,12-octadecanoic acid 5.06%, 3-eicosyne 4.75%, 1-hexadecenoic acid 4.08%, 11-tetradecen-1-ol 2.92%, 2-furanmethanol 2.83%, delta-guaiene 2.43%, cyclohexane 2.13%, hexadecanoic acid 1.99%, sativen 1.87%, octadecanoic acid 1.52%, 1H-cyclopropaanaphthalene 1.40%, tetradecanoic acid 1.40%, 3,7,11-tridecatrienenitrile 1.20%, caryophellene 1.11%, 2H-pyran 1.07%, and trans-caryophellene 1.03%. This study clearly shows the presence of fatty acids which play a major role in the efficacy of these traditional medicines particularly as antioxidant and antimalarial.
马六甲（）是印度尼西亚亚齐省地区社区常用的植物之一，作为治疗各种疾病的传统药物，如抗菌、抗菌、抗真菌、抗病毒、抗诱变、抗疟疾和抗过敏。本研究旨在使用气相色谱 - 质谱仪（GC - MS）分析马六甲叶乙醇提取物（EEDM）中的化学成分。马六甲叶采用浸渍法，分别用正己烷、乙酸乙酯和乙醇进行提取。GC - MS分析表明EEDM含有22种化合物。EEDM中含量最高的化学成分是十八烷酸，达到22.93%，9,12 - 十八碳二烯酸14.99%，十八烷酸7.59%，9 - 十六碳烯酸6.17%，十八烷酸5.95%，十八醛5.59%，9,12 - 十八碳二烯酸5.06%，3 - 二十碳炔4.75%，1 - 十六碳烯酸4.08%，11 - 十四碳烯 - 1 - 醇2.92%，2 - 呋喃甲醇2.83%，δ - 愈创木烯2.43%，环己烷2.13%，十六烷酸1.99%，蛇床烯1.87%，十八烷酸1.52%，1H - 环丙并萘1.40%，十四烷酸1.40%，3,7,11 - 十三碳三烯腈1.20%，石竹烯1.11%，2H - 吡喃1.07%，反式石竹烯1.
