College of Food Science and Engineering, Hainan University, No.38, Renming Road, Meilan District, Haikou, China.
Laboratory of Quality and Safety Risk Assessment for Agro-Products (Haikou), Ministry of Agriculture, Haikou, China.
J Sci Food Agric. 2020 Sep;100(12):4540-4548. doi: 10.1002/jsfa.10495. Epub 2020 Jun 3.
Cyromazine and acetamiprid are widely applied as pesticides in agriculture, causing increasing concerns about their residues in crops. In this study, cyromazine, acetamiprid and their mixture were applied to cowpea to investigate their degradation dynamics and perform a dietary risk assessment.
The dissipation behavior of cyromazine and acetamiprid in the single- and mixed-pesticide groups followed first-order kinetics, with a linear correlation coefficient of 0.910 to 0.987. The half-lives of cyromazine and acetamiprid were 1.56-11.18 days in the four different matrices. The half-life of cyromazine in the mixed-pesticide group was similar to or even shorter than that in the single-pesticide group. The highest levels of cyromazine and acetamiprid in cowpea occurred with a preharvest interval of 7 days and after two or three applications. These levels are below the maximum residue limits recommended by the Chinese Ministry of Agriculture for cyromazine and acetamiprid in cowpea. The risk quotient of cyromazine and acetamiprid ranged from 0.0018 to 0.0418, and the national estimated short-term intake values of the cyromazine and acetamiprid were far below the acute reference dose as recommended by the European Food Safety Authority.
These results suggest that the use of cyromazine and acetamiprid and a cyromazine-acetamiprid mixture in cowpea is safe under the Good Agricultural Practices for Chinese fields, and the use of a cyromazine-acetamiprid mixture affords even better results than the application of cyromazine alone. Moreover, the residue dynamics information will support the label claims for the application of cyromazine, acetamiprid and a cyromazine-acetamiprid mixture to cowpea fruit. © 2020 Society of Chemical Industry.
环丙氨嗪和乙酰甲胺磷作为农药在农业中广泛应用，其在作物中的残留问题引起了越来越多的关注。本研究将环丙氨嗪、乙酰甲胺磷及其混剂施用于豇豆，以考察其在豇豆中的降解动态，并进行膳食风险评估。
环丙氨嗪和乙酰甲胺磷在单剂和混剂处理组中的消解行为均符合一级动力学方程，相关系数为 0.910 至 0.987。在 4 种不同基质中环丙氨嗪和乙酰甲胺磷的半衰期为 1.56-11.18 天。混剂处理组中环丙氨嗪的半衰期与单剂处理组相似甚至更短。在预收获间隔 7 天、使用 2-3 次后，豇豆中检测到的环丙氨嗪和乙酰甲胺磷的最高残留量均低于中国农业部推荐的环丙氨嗪和乙酰甲胺磷在豇豆中的最大残留限量。环丙氨嗪和乙酰甲胺磷的风险商数在 0.0018 至 0.0418 之间，国家估算的环丙氨嗪和乙酰甲胺磷短期摄入量远低于欧洲食品安全局推荐的急性参考剂量。
这些结果表明，在中国田间良好农业规范下，使用环丙氨嗪和乙酰甲胺磷及其混剂处理豇豆是安全的，而且使用环丙氨嗪-乙酰甲胺磷混剂的效果甚至优于单独使用环丙氨嗪。此外，残留动态信息将支持环丙氨嗪、乙酰甲胺磷及其混剂在豇豆果实上使用的标签说明。 © 2020 英国化学学会。
