1Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio.
2Schistosomiasis Consortium for Operational Research and Evaluation, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Am J Trop Med Hyg. 2020 Jul;103(1_Suppl):92-96. doi: 10.4269/ajtmh.19-0806.
The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was established in late 2008 to conduct operational research to inform global health practices related to the control and elimination of schistosomiasis. The greatest part of the SCORE investment has been in multiyear, long-term efforts, including cluster-randomized trials of gaining and sustaining control of schistosomiasis, trials on elimination of schistosomiasis, and diagnostic test development and evaluation. In the course of planning and conducting SCORE studies, critical questions were raised that could be answered relatively quickly by collecting, collating, and synthesizing existing data. Through its Rapid Answers Project (RAP), the SCORE conducted seven systematic reviews, including four associated meta-analyses, on issues related to screening for schistosomiasis, enhancing mass drug administration, treatment impacts, and the efficacy of snail control for prevention of human schistosomiasis. This article summarizes the findings of the seven RAP reports and provides links to the studies and their supporting information.
血吸虫病操作研究和评价合作组织（SCORE）成立于 2008 年末，旨在开展操作研究，为与控制和消除血吸虫病相关的全球卫生实践提供信息。SCORE 的最大投资部分是多年的长期努力，包括获得和维持血吸虫病控制的集群随机试验、消除血吸虫病的试验以及诊断测试的开发和评估。在规划和进行 SCORE 研究的过程中，提出了一些关键问题，可以通过收集、整理和综合现有数据来快速回答。通过其快速回答项目（RAP），SCORE 就与血吸虫病筛查、增强大规模药物治疗、治疗效果以及钉螺控制预防人类血吸虫病的效果相关的问题进行了七项系统评价，其中包括四项相关的荟萃分析。本文总结了七项 RAP 报告的调查结果，并提供了与这些研究及其支持信息的链接。
