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新型中国糖尿病风险评分在中国东部社区人群中筛查未诊断 2 型糖尿病和糖尿病前期的效果:一项基于社区的横断面研究。

The Efficacy of New Chinese Diabetes Risk Score in Screening Undiagnosed Type 2 Diabetes and Prediabetes: A Community-Based Cross-Sectional Study in Eastern China.

机构信息

Department of Health Education, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.

School of Public Health, Nanchang University, Nanchang 330006, China.

出版信息

J Diabetes Res. 2020 Apr 29;2020:7463082. doi: 10.1155/2020/7463082. eCollection 2020.

Abstract

The New Chinese Diabetes Risk Score (NCDRS) is one of the recommended tools for screening undiagnosed type 2 diabetes in China. However, its performance in detecting undiagnosed diabetes needs to be verified in different community populations. Also, it is unknown whether NCDRS can be used in detecting prediabetes. In the present study, we aimed to evaluate the performance of NCDRS in detecting undiagnosed diabetes and prediabetes among the community residents in eastern China. We applied NCDRS in 7675 community residents aged 18-65 years old in Jiangsu Province. The results showed that the participants with undiagnosed diabetes reported the highest NCDRS value, followed by those with prediabetes ( < 0.001). The best cut-off points of NCDRS for detecting undiagnosed diabetes and prediabetes were 27 (with a sensitivity of 78.0% and a specificity of 57.7%) and 27 (with a sensitivity of 66.0% and a specificity of 62.9%). The AUCs of NCDRS for identifying undiagnosed diabetes and prediabetes were 0.749 (95% CI: 0.7390.759) and 0.694 (95% CI: 0.6830.705). These results demonstrate the excellent performance of NCDRS in screening undiagnosed diabetes in the community population in eastern China and further provide evidence for using NCDRS in detecting prediabetes.

摘要

新的中国糖尿病风险评分(NCDRS)是中国推荐用于筛查未诊断的 2 型糖尿病的工具之一。然而,其在不同社区人群中检测未诊断糖尿病的性能需要得到验证。此外,尚不清楚 NCDRS 是否可用于检测糖尿病前期。在本研究中,我们旨在评估 NCDRS 在检测中国东部社区居民中未诊断糖尿病和糖尿病前期的性能。我们将 NCDRS 应用于江苏省 7675 名年龄在 18-65 岁的社区居民。结果表明,患有未诊断糖尿病的参与者报告的 NCDRS 值最高,其次是患有糖尿病前期的参与者(<0.001)。用于检测未诊断糖尿病和糖尿病前期的 NCDRS 的最佳截断值分别为 27(敏感性为 78.0%,特异性为 57.7%)和 27(敏感性为 66.0%,特异性为 62.9%)。NCDRS 用于识别未诊断糖尿病和糖尿病前期的 AUC 分别为 0.749(95%CI:0.7390.759)和 0.694(95%CI:0.6830.705)。这些结果表明 NCDRS 在筛查中国东部社区人群中未诊断糖尿病方面具有出色的性能,并进一步为使用 NCDRS 检测糖尿病前期提供了证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3da1/7210548/fb0e65c75e4b/JDR2020-7463082.001.jpg

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