Department of Chemistry, Pusan National University, Busan, 46241, South Korea.
Department of Industrial Chemistry, Alagappa University, Karaikudi, 630003, Tamil Nadu, India.
Anal Chim Acta. 2020 Jun 29;1118:26-35. doi: 10.1016/j.aca.2020.04.043. Epub 2020 Apr 21.
We reported the synthesis of a copolymer- and metal-organic framework-based electrochemical sensor, UiO-66-NH@P(ANI-co-ANA) using the polymerization method for the highly sensitive and selective detection of hydrogen peroxide (HO) and dopamine (DA). The as-synthesized material was characterized via Fourier transform infrared spectroscopy, X-ray diffraction analysis, scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, and thermogravimetric analysis. The electrochemical characteristics of the proposed sensor were evaluated via impedance spectroscopy and cyclic voltammetry (CV). The electrochemical oxidation of DA and the reduction of HO were determined via CV, square-wave voltammetry, and chronoamperometric techniques. The fabricated sensor exhibited a wide linear range of 25-500 μM, with a sensitivity of 1396.1 μAμMcm and a limit of detection of 0.6 μM, for the electrochemical reduction of HO. Additionally, it exhibited a wide linear range of 10-110 μM, with a sensitivity of 1110.2 μAμMcm and a limit of detection of 0.3 μM, for the electrochemical detection of DA. The practical utility of the fabricated sensor was evaluated via the detection of HO in milk samples and DA in human urine samples.
我们报道了一种基于共聚物和金属有机骨架的电化学传感器 UiO-66-NH@P(ANI-co-ANA)的合成，该传感器采用聚合方法用于高灵敏度和选择性检测过氧化氢（HO）和多巴胺（DA）。所合成的材料通过傅里叶变换红外光谱、X 射线衍射分析、扫描电子显微镜、透射电子显微镜、X 射线光电子能谱和热重分析进行了表征。通过阻抗谱和循环伏安法（CV）评估了所提出传感器的电化学特性。通过 CV、方波伏安法和计时安培法测定了 DA 的电化学氧化和 HO 的还原。所制备的传感器在 HO 的电化学还原中表现出宽线性范围为 25-500 μM，灵敏度为 1396.1 μAμMcm，检测限为 0.6 μM。此外，它在 DA 的电化学检测中表现出宽线性范围为 10-110 μM，灵敏度为 1110.2 μAμMcm，检测限为 0.3 μM。通过在牛奶样品中检测 HO 和在人尿样品中检测 DA，评估了所制备传感器的实际应用。
