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基于电化学的多孔金属有机骨架用于葡萄糖和 HO 检测的传感平台:现状与展望综述。

Electrochemical-Based Sensing Platforms for Detection of Glucose and HO by Porous Metal-Organic Frameworks: A Review of Status and Prospects.

机构信息

Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz 51666-16471, Iran.

Department of Biology, Tabriz Branch, Islamic Azad University, Tabriz 51666-16471, Iran.

出版信息

Biosensors (Basel). 2023 Mar 4;13(3):347. doi: 10.3390/bios13030347.

Abstract

Establishing enzyme-free sensing assays with great selectivity and sensitivity for glucose and HO detection has been highly required in biological science. In particular, the exploitation of nanomaterials by using noble metals of high conductivity and surface area has been widely investigated to act as selective catalytic agents for molecular recognition in sensing platforms. Several approaches for a straightforward, speedy, selective, and sensitive recognition of glucose and HO were requested. This paper reviews the current progress in electrochemical detection using metal-organic frameworks (MOFs) for HO and glucose recognition. We have reviewed the latest electrochemical sensing assays for in-place detection with priorities including straightforward procedure and manipulation, high sensitivity, varied linear range, and economic prospects. The mentioned sensing assays apply electrochemical systems through a rapid detection time that enables real-time recognition. In profitable fields, the obstacles that have been associated with sample preparation and tool expense can be solved by applying these sensing means. Some parameters, including the impedance, intensity, and potential difference measurement methods have permitted low limit of detections (LODs) and noticeable durations in agricultural, water, and foodstuff samples with high levels of glucose and HO.

摘要

在生物科学领域,人们非常需要建立具有高选择性和灵敏度的无酶传感分析方法来检测葡萄糖和 HO。特别是,利用导电性和表面积高的贵金属的纳米材料作为传感平台中的分子识别的选择性催化试剂已得到广泛研究。人们需要几种方法来直接、快速、选择性和灵敏地识别葡萄糖和 HO。本文综述了用于 HO 和葡萄糖识别的金属有机框架(MOF)的电化学检测的最新进展。我们综述了最新的电化学传感分析方法,用于原位检测,重点包括简单的程序和操作、高灵敏度、宽线性范围和经济前景。所提到的传感分析方法通过快速检测时间应用电化学系统,从而实现实时识别。在有利可图的领域,通过应用这些传感手段,可以解决与样品制备和工具费用相关的障碍。一些参数,包括阻抗、强度和电位差测量方法,已在葡萄糖和 HO 含量高的农业、水和食品样品中实现了低检测限(LOD)和显著的检测时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24db/10046199/073223a32341/biosensors-13-00347-sch001.jpg

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