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有酗酒家族史的非酗酒男性对酒精的行为和脑电图反应。

Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism.

作者信息

Kaplan R F, Hesselbrock V M, O'Connor S, DePalma N

机构信息

Department of Psychiatry, University of Connecticut Health Center, Farmington.

出版信息

Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(6):873-85. doi: 10.1016/0278-5846(88)90083-8.

DOI:10.1016/0278-5846(88)90083-8
PMID:3241870
Abstract
  1. Behavioral and EEG responses were examined in nonalcoholic males with (FH+) and without (FH-) a family history of alcoholism following the consumption of a placebo and real beer. 2. FH+ subjects were less confident of being able to resist another drink following consumption of the placebo and reported higher taste ratings and feeling more intoxicated immediately following ethanol consumption than FH- subjects. 3. Both groups showed increases in EEG alpha activity (9-12Hz) following alcohol consumption. 4. Alpha activity was positively associated with desire to drink in the FH+ group before and after consumption, but was positively associated with perceived intoxication in the FH- group only after consumption.
摘要
  1. 在饮用安慰剂和真正的啤酒后,对有(FH+)和没有(FH-)酗酒家族史的非酒精性男性的行为和脑电图反应进行了检查。2. FH+受试者在饮用安慰剂后对能够拒绝再喝一杯的信心较低,并且在饮用乙醇后报告的口味评分更高,并且比FH-受试者感觉更醉。3. 两组在饮酒后脑电图α活动(9-12Hz)均增加。4. 在FH+组中,饮用前后α活动与饮酒欲望呈正相关,但在FH-组中,α活动仅在饮用后与感知到的醉酒程度呈正相关。

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Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(6):873-85. doi: 10.1016/0278-5846(88)90083-8.
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