Grupo Infecciones y Salud en el Trópico, Universidad Nacional de Colombia, Bogotá, Colombia.
Grupo de Epidemiología y Evaluación en Salud pública, Universidad Nacional de Colombia, Bogotá, Colombia; Grupo Medicina Comunitaria y Salud Colectiva, Universidad El Bosque, Bogotá, Colombia; Coordinación de Epidemiología e Investigación, Los Cobos Medical Center. Bogotá, Colombia.
Int J Infect Dis. 2020 Aug;97:81-89. doi: 10.1016/j.ijid.2020.05.051. Epub 2020 May 17.
During the 2013-2016 period, Dengue, Chikungunya, and Zika affected more than 1 million people in Colombia. These arboviruses and their chronic manifestations pose a public health challenge. Therefore, we estimated the burden of disease by Dengue, Chikungunya, and Zika in Colombia between 2013 and 2016.
An exploratory ecological study was carried out using the disability-adjusted life years (DALYs) as a unit of measure. The mortality databases of the National Administrative Department of Statistics (DANE) and the morbidity databases of the National Public Health Surveillance System (SIVIGILA) were used. Deaths and cases for each arbovirus were grouped and then adjusted to control biases. Subsequently, we performed a sensitivity analysis.
In the 2013-2016 period, 491,629.2 DALYs were lost due to arboviruses in Colombia. By disease, 26.6% of the total DALYs were caused by Dengue, 71.3% by Chikungunya, and the remaining 2.2%, by Zika. The majority of DALYs (68.2%) were caused by chronic complications. Five out of 32 departments (Valle del Cauca, Tolima, Norte de Santander, Huila, and Bolívar) contributed 50.5% of total DALYs.
The burden of disease by arboviruses in the 2013-2016 period exceeded the burden of other infectious diseases such as HIV/AIDS and tuberculosis in Colombia. Public health efforts must be made to mitigate new epidemics of these arboviruses.
2013-2016 年期间，登革热、基孔肯雅热和寨卡热在哥伦比亚影响了超过 100 万人。这些虫媒病毒及其慢性表现构成了公共卫生挑战。因此，我们估计了 2013 年至 2016 年期间哥伦比亚登革热、基孔肯雅热和寨卡热的疾病负担。
采用残疾调整生命年（DALY）作为衡量单位进行探索性生态研究。使用国家行政统计局（DANE）的死亡率数据库和国家公共卫生监测系统（SIVIGILA）的发病率数据库。将每种虫媒病毒的死亡和病例进行分组，然后进行调整以控制偏差。随后，我们进行了敏感性分析。
在 2013-2016 年期间，哥伦比亚因虫媒病毒而损失了 491629.2 DALY。按疾病分类，26.6%的总 DALY 由登革热引起，71.3%由基孔肯雅热引起，其余 2.2%由寨卡热引起。大多数 DALY（68.2%）是由慢性并发症引起的。在 32 个部门中，有 5 个部门（考卡山谷、托利马、北桑坦德、胡拉和玻利瓦尔）占总 DALY 的 50.5%。
2013-2016 年期间，虫媒病毒疾病负担超过了哥伦比亚其他传染病（如艾滋病毒/艾滋病和结核病）的负担。必须采取公共卫生措施，以减轻这些虫媒病毒的新流行。
