• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

水飞蓟素及其衍生物：从生物合成到健康益处。

Silymarin and Derivatives: From Biosynthesis to Health Benefits.

机构信息

Faculty of Health Sciences, University of Bourgogne, 7 bd Jeanne d'Arc, F-21000 Dijon, France.

INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, F-21000 Dijon, France.

出版信息

Molecules. 2020 May 22;25(10):2415. doi: 10.3390/molecules25102415.

DOI:10.3390/molecules25102415
PMID:32455869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7287892/
Abstract

The past decade has been marked by an intense scientific interest in the use of compounds or micronutrients of natural origin and their potential effects on human health, both from researchers and industry [...].

摘要

过去十年，科学界对天然来源的化合物或微量营养素及其对人类健康的潜在影响产生了浓厚的兴趣，研究人员和企业都纷纷投入其中[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a3d/7287892/1b8c327c134f/molecules-25-02415-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a3d/7287892/1b8c327c134f/molecules-25-02415-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a3d/7287892/1b8c327c134f/molecules-25-02415-g001.jpg

相似文献

1
Silymarin and Derivatives: From Biosynthesis to Health Benefits.水飞蓟素及其衍生物：从生物合成到健康益处。
Molecules. 2020 May 22;25(10):2415. doi: 10.3390/molecules25102415.
2
[Silymarin in the treatment of chronic liver diseases: past and future].[水飞蓟素治疗慢性肝病：过去与未来]
Orv Hetil. 2008 Dec 21;149(51):2413-8. doi: 10.1556/OH.2008.28519.
3
Biotransformation of silybin and its congeners.水飞蓟宾及其同系物的生物转化。
Curr Drug Metab. 2013 Dec;14(10):1009-21. doi: 10.2174/1389200214666131118234507.
4
Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years.水飞蓟素/水飞蓟宾与慢性肝病：多年的结合
Molecules. 2017 Jan 24;22(2):191. doi: 10.3390/molecules22020191.
5
A comparative study on the stability of silybin and that in silymarin in buffers and biological fluids.水飞蓟宾与水飞蓟素在缓冲液和生物流体中的稳定性比较研究。
Drug Metab Lett. 2009 Apr;3(2):115-9. doi: 10.2174/187231209788654072.
6
New C-23 modified of silybin and 2,3-dehydrosilybin: synthesis and preliminary evaluation of antioxidant properties.新型 C-23 修饰的水飞蓟宾和 2,3-脱水水飞蓟宾：合成及抗氧化性能的初步评价。
Bioorg Med Chem Lett. 2011 Aug 1;21(15):4389-92. doi: 10.1016/j.bmcl.2011.06.049. Epub 2011 Jun 17.
7
Silymarin and Its Role in Chronic Diseases.水飞蓟素及其在慢性病中的作用。
Adv Exp Med Biol. 2016;929:25-44. doi: 10.1007/978-3-319-41342-6_2.
8
A biomimetic strategy to access the silybins: total synthesis of (-)-isosilybin A.一种获取水飞蓟宾的仿生策略：(-)-异水飞蓟宾A的全合成。
Org Lett. 2015 Jan 2;17(1):98-101. doi: 10.1021/ol503303w. Epub 2014 Dec 17.
9
Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review.水飞蓟素与肝细胞癌：一项系统、全面且批判性的综述
Anticancer Drugs. 2015 Jun;26(5):475-86. doi: 10.1097/CAD.0000000000000211.
10
Recent advances in the nanotechnology-based drug delivery of Silybin.基于纳米技术的水飞蓟宾药物递送的最新进展。
J Biomed Nanotechnol. 2014 Apr;10(4):543-58. doi: 10.1166/jbn.2014.1798.

引用本文的文献

1
Cold-Active Lipase from the Ice Cave SC65A.3 Strain, a Promising Biocatalyst for Silybin Acylation.来自冰洞 SC65A.3 菌株的冷活性脂肪酶，是水飞蓟宾酰化的有前途的生物催化剂。
Molecules. 2024 Oct 30;29(21):5125. doi: 10.3390/molecules29215125.
2
Impacts of Supplementation with Silymarin on Cardiovascular Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.水飞蓟素补充剂对心血管危险因素的影响：系统评价与剂量反应荟萃分析。
Antioxidants (Basel). 2024 Mar 24;13(4):390. doi: 10.3390/antiox13040390.
3
Efficacy and Mechanisms of , Silymarin, and Silibinin on Rheumatoid Arthritis and Osteoarthritis Symptoms: A Systematic Review.

本文引用的文献

1
Silymarin and Cancer: A Dual Strategy in Both in Chemoprevention and Chemosensitivity.水飞蓟素与癌症：化学预防和化学敏感性方面的双重策略
Molecules. 2020 Apr 25;25(9):2009. doi: 10.3390/molecules25092009.
2
Metabolism, Transport and Drug-Drug Interactions of Silymarin.水飞蓟素的代谢、转运和药物相互作用。
Molecules. 2019 Oct 14;24(20):3693. doi: 10.3390/molecules24203693.
3
Formulation Strategies for Enhancing the Bioavailability of Silymarin: The State of the Art.水飞蓟素生物利用度增强的制剂策略：最新进展。
水飞蓟素、水飞蓟宾及奶蓟草提取物治疗类风湿关节炎和骨关节炎症状的疗效及作用机制：系统评价。
Curr Rheumatol Rev. 2024;20(4):414-425. doi: 10.2174/0115733971266397231122080247.
4
Co-treatment of silymarin and cisplatin inhibited cell proliferation, induced apoptosis in ovarian cancer.水飞蓟素与顺铂联合治疗可抑制卵巢癌细胞增殖，诱导其凋亡。
Mol Biol Rep. 2024 Jan 16;51(1):118. doi: 10.1007/s11033-023-09026-8.
5
Tannic Acid, A Hydrolysable Tannin, Prevents Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition to Counteract Colorectal Tumor Growth.鞣酸，一种可水解的单宁，可防止转化生长因子-β诱导的上皮-间充质转化，从而抑制结直肠肿瘤生长。
Cells. 2022 Nov 17;11(22):3645. doi: 10.3390/cells11223645.
6
Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions.水飞蓟素在癌症治疗中的作用：事实、假设和问题。
J Evid Based Integr Med. 2022 Jan-Dec;27:2515690X211068826. doi: 10.1177/2515690X211068826.
7
Phyto-pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for COVID-19, based on its promising immunomodulatory, anti-coagulant and anti-viral property.水飞蓟宾的植物药理学视角：基于其有前景的免疫调节、抗凝和抗病毒特性，作为 COVID-19 的潜在预防或治疗剂。
Phytother Res. 2021 Aug;35(8):4246-4257. doi: 10.1002/ptr.7084. Epub 2021 Apr 4.
8
Plants of the Spontaneous Flora with Beneficial Action in the Management of Diabetes, Hepatic Disorders, and Cardiovascular Disease.对糖尿病、肝脏疾病和心血管疾病治疗具有有益作用的自然植物区系植物。
Plants (Basel). 2021 Jan 23;10(2):216. doi: 10.3390/plants10020216.
Molecules. 2019 Jun 7;24(11):2155. doi: 10.3390/molecules24112155.
4
Silymarin's Inhibition and Treatment Effects for Alzheimer's Disease.水飞蓟素对阿尔茨海默病的抑制和治疗作用。
Molecules. 2019 May 6;24(9):1748. doi: 10.3390/molecules24091748.
5
Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin.纳米胶束制剂提高水飞蓟宾的溶解度和口服吸收。
Molecules. 2019 Apr 30;24(9):1688. doi: 10.3390/molecules24091688.
6
Silymarin: Friend or Foe of UV Exposed Keratinocytes?水飞蓟素：紫外线暴露的角质形成细胞的朋友还是敌人？
Molecules. 2019 Apr 26;24(9):1652. doi: 10.3390/molecules24091652.
7
Antiviral Activities of Silymarin and Derivatives.水飞蓟素及其衍生物的抗病毒活性。
Molecules. 2019 Apr 19;24(8):1552. doi: 10.3390/molecules24081552.
8
Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia.水飞蓟宾下调子痫前期孕妇单核细胞中 NF-κB 通路和 NLRP1/NLRP3 炎性体。
Molecules. 2019 Apr 19;24(8):1548. doi: 10.3390/molecules24081548.
9
A Water-Soluble Microencapsulated Milk Thistle Extract as Active Ingredient for Dermal Formulations.水包油型微胶囊化奶蓟草提取物作为一种用于皮肤制剂的活性成分。
Molecules. 2019 Apr 19;24(8):1547. doi: 10.3390/molecules24081547.
10
Silybin Modulates Collagen Turnover in an In Vitro Model of NASH.水飞蓟宾在非酒精性脂肪性肝炎的体外模型中调节胶原代谢。
Molecules. 2019 Apr 2;24(7):1280. doi: 10.3390/molecules24071280.