Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, Korea.
Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2020 Jun 1;35(21):e199. doi: 10.3346/jkms.2020.35.e199.
The world is currently experiencing a pandemic of coronavirus disease 2019 (COVID-19). In Korea, as in other countries, the number of confirmed cases and deaths due to COVID-19 have been rising. This study aimed to calculate the burden of disease due to COVID-19 in Korea.
We used data on confirmed cases and deaths due to COVID-19 between January 20 and April 24, 2020 provided by the Korea Centers for Disease Control and Prevention, the local governments and the public media to determine disability-adjusted life years (DALYs) by sex and age. Morbidity was estimated directly among the confirmed, cured, and fatal cases. Disability weights were adopted from previous similar causes on the severity of COVID-19 for the years of life lived with disability (YLDs). The years of life lost (YLLs) were calculated using the standard life expectancy from the 2018 life tables for each sex and age.
The YLDs were higher in females (155.2) than in males (105.1), but the YLLs were higher in males (1,274.3) than in females (996.4). The total disease burden attributable to COVID-19 in Korea during the study period, was estimated to be 2,531.0 DALYs, and 4.930 DALYs per 100,000 population. The YLDs and the YLLs constituted 10.3% and 89.7% of the total DALYs, respectively. The DALYs per 100,000 population were highest in people aged ≥ 80 years, followed by those aged 70-79, 60-69, and 50-59 years, but the incidence was the highest in individuals aged 20-29 years.
This study provided the estimates of DALYs due to COVID-19 in Korea. Most of the disease burden from COVID-19 was derived from YLL; this indicates that decision-makers should focus and make an effort on reducing fatality for preparing the second wave of COVID-19.
目前,全球正面临 2019 年冠状病毒病(COVID-19)大流行。在韩国,与其他国家一样,COVID-19 确诊病例和死亡人数持续上升。本研究旨在计算韩国 COVID-19 疾病负担。
我们使用韩国疾病控制和预防中心、地方政府和公共媒体提供的 2020 年 1 月 20 日至 4 月 24 日期间 COVID-19 确诊病例和死亡数据,按性别和年龄计算伤残调整生命年(DALY)。发病率通过确诊病例、治愈病例和死亡病例直接估计。使用因 COVID-19 严重程度与以往类似疾病的残疾权重计算因残疾导致的生命年损失(YLDs)。根据各性别和年龄的 2018 年生命表计算损失的生命年(YLLs)。
女性的 YLDs(155.2)高于男性(105.1),但男性的 YLLs(1274.3)高于女性(996.4)。研究期间,韩国 COVID-19 造成的总疾病负担估计为 2531.0 DALY,每 10 万人中有 4.930 DALY。YLDs 和 YLLs 分别占总 DALYs 的 10.3%和 89.7%。每 10 万人的 DALY 最高的是年龄≥80 岁的人群,其次是 70-79 岁、60-69 岁和 50-59 岁的人群,而发病率最高的是 20-29 岁的人群。
本研究提供了韩国 COVID-19 疾病负担的估计。COVID-19 的疾病负担主要来自 YLL,这表明决策者应集中精力减少病死率,为应对 COVID-19 的第二波疫情做准备。