高发病率国家中与 COVID-19 相关的寿命损失年数。

Years of Life Lost Attributable to COVID-19 in High-incidence Countries.

机构信息

Department of Preventive Medicine, School of Medicine, Kyung Hee University, Seoul, Korea.

Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2020 Aug 17;35(32):e300. doi: 10.3346/jkms.2020.35.e300.

Abstract

BACKGROUND

The coronavirus disease 2019 (COVID-19) pandemic is a major public health problem of international concern. It is important to estimate its impact of COVID-19 for health policy decision-making. We estimated the years of life lost (YLLs) due to COVID-19 in high-incidence countries.

METHODS

We collected the YLLs due to COVID-19 in 30 high-incidence countries as of April 13, 2020 and followed up as of July 14, 2020. Incidence and mortality were collected using each country's formal reports, articles, and other electronic sources. The life expectancy of Japanese females by age and the UN population data were used to calculate YLLs in total and per 100,000.

RESULTS

As of April 22, 2020, there were 1,699,574 YLLs due to COVID-19 in 30 high-incidence countries. On July 14, 2020, this increased to 4,072,325. Both on April 22 and July 14, the total YLLs due to COVID-19 was highest in the USA (April 22, 534,481 YLLs; July 14, 1,199,510 YLLs), and the YLLs per 100,000 population was highest in Belgium (April 22, 868.12 YLLs/100,000; July 14, 1,593.72 YLLs/100,000). YLLs due to COVID-19 were higher among males than among females and higher in those aged ≥ 60 years than in younger individuals. Belgium had the highest proportion of YLLs attributable to COVID-19 as a proportion of the total YLLs and the highest disability-adjusted life years per 100,000 population.

CONCLUSION

This study estimated YLLs due to COVID-19 in 30 countries. COVID-19 is a high burden in the USA and Belgium, among males and the elderly. The YLLs are very closely related with the incidence as well as the mortality. This highlights the importance of the early detection of incident case that minimizes severe acute respiratory syndrome coronavirus-2 fatality.

摘要

背景

2019 年冠状病毒病(COVID-19)大流行是一个国际关注的主要公共卫生问题。为了卫生政策决策,评估其对 COVID-19 的影响很重要。我们估计了高发病率国家因 COVID-19 而导致的生命损失年数(YLL)。

方法

我们收集了截至 2020 年 4 月 13 日 30 个高发病率国家的 COVID-19 所致 YLL,并随访至 2020 年 7 月 14 日。发病率和死亡率使用每个国家的正式报告、文章和其他电子来源收集。使用日本女性的年龄别预期寿命和联合国人口数据计算了总 YLL 和每 10 万人的 YLL。

结果

截至 2020 年 4 月 22 日,30 个高发病率国家因 COVID-19 导致的 YLL 为 1699574 例。到 2020 年 7 月 14 日,这一数字增加到 4072325 例。无论是在 4 月 22 日还是 7 月 14 日,美国的 COVID-19 总 YLL 最高(4 月 22 日为 534481 例 YLL;7 月 14 日为 1199510 例 YLL),每 10 万人的 YLL 最高的是比利时(4 月 22 日为 868.12 例 YLL/10 万人;7 月 14 日为 1593.72 例 YLL/10 万人)。COVID-19 所致 YLL 男性高于女性,≥60 岁者高于年轻者。比利时 COVID-19 所致 YLL 占总 YLL 的比例最高,每 10 万人的伤残调整生命年也最高。

结论

本研究估计了 30 个国家 COVID-19 所致 YLL。美国和比利时的 COVID-19 负担沉重,男性和老年人的负担更重。YLL 与发病率和死亡率密切相关。这突出表明,早期发现可最大限度减少严重急性呼吸综合征冠状病毒 2 死亡率的确诊病例的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624f/7431288/af11690f9fc1/jkms-35-e300-g001.jpg

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