非结核分枝杆菌肺病：一项意大利全国性调查。
Non-tuberculous mycobacterial pulmonary disease: an Italian National survey.
作者信息
Prato Bruno Del, Altieri Alfonso Maria, Carlucci Biagio, Mori Pier Anselmo, Parrella Roberto, Stainer Anna, Giacomi Federica De, Pesci Alberto, Faverio Paola
机构信息
U.O.S.C. Pneumologia Interventistica A.O.R.N.A. Cardarelli, Napoli, Italy.
U.O.C. Broncopneumologia e Tisiologia, A.O. S. Camillo-Forlanini, Roma, Italy.
出版信息
Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(1):21-25. doi: 10.36141/svdld.v35i1.6979. Epub 2018 Apr 28.
The incidence of non-tuberculous mycobacteria (NTM) infection is increasing in Europe. However, a picture of Italian epidemiology and clinical practice is missing. We performed a national Italian survey involving 42 respiratory medicine departments. The NTM species more frequently isolated were , followed by and . Patients with NTM were more frequently female (57%), and over 60 years of age, with bronchiectasis and COPD as main comorbidities. Bronchoscopic samples were widely used in the diagnostic phase. Of all patients with NTM, 73% met the criteria for NTM pulmonary disease. Despite strong adherence to the guidelines, physicians found significant difficulties related to pharmacological adverse events, patients' compliance and poor outcomes. .
在欧洲，非结核分枝杆菌（NTM）感染的发病率正在上升。然而，目前尚缺乏意大利的流行病学和临床实践情况。我们在意大利开展了一项全国性调查，涉及42个呼吸内科。最常分离出的NTM菌种依次为 ，其次是 和 。NTM患者中女性更为常见（57%），年龄多在60岁以上，主要合并症为支气管扩张和慢性阻塞性肺疾病（COPD）。支气管镜检查样本在诊断阶段被广泛使用。在所有NTM患者中，73%符合NTM肺病的标准。尽管严格遵循指南，但医生们在药物不良事件、患者依从性和疗效不佳方面仍遇到了重大困难。
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