植物提取物介导的合成比化学介导的合成增强了铁酸银纳米颗粒的功能特性。

Plant extract mediated synthesis enhanced the functional properties of silver ferrite nanoparticles over chemical mediated synthesis.

作者信息

Muthukumar Harshiny, Palanirajan Santosh Kumar, Shanmugam Manoj Kumar, Gummadi Sathyanarayana N

机构信息

Applied and Industrial Microbiology Lab, Department of Biotechnology, Indian Institute of Technology Madras, Chennai, 600036, India.

出版信息

Biotechnol Rep (Amst). 2020 May 15;26:e00469. doi: 10.1016/j.btre.2020.e00469. eCollection 2020 Jun.

In this study, the antibacterial, antioxidant and cytotoxicity behaviour of silver ferrite nanoparticles (AgFeO2 NPs) synthesized through chemical and green routes were compared. Green synthesis (Bio) of AgFeO2 NPs were prepared by precipitation method using Amaranthus blitum leaves extract as a reducing agent. Chemical synthesis (Che) of AgFeO2 NPs was mediated by sodium borohydride as a reducing agent. [AgFeO2 (Bio)] NPs showed reduced size, better monodispersity and surface area compared to [AgFeO2 (Che)] NPs. The results showed that synthesized NPs have better antibacterial activity against E. coli than S. aureus. In addition, 250 μg of AgFeO2 (Bio) and (Che) NPs showed antioxidant efﬁciency of 98 and 86%. The results showed that [AgFeO2 (Bio)] NPs showed lower cytotoxicity [AgFeO2 (Che)] NPs against human human embryonic kidney (HEK 293) cells. These results suggest that [AgFeO2 (Bio)] NPs have improved physicochemical properties thereby they can be used as an effective biocatalytic material in biotechnology.

在本研究中，比较了通过化学和绿色途径合成的银铁氧体纳米颗粒（AgFeO₂ NPs）的抗菌、抗氧化和细胞毒性行为。以皱果苋叶提取物为还原剂，采用沉淀法制备了绿色合成（Bio）的AgFeO₂ NPs。以硼氢化钠为还原剂介导了AgFeO₂ NPs的化学合成（Che）。与[AgFeO₂（Che）] NPs相比，[AgFeO₂（Bio）] NPs尺寸更小、单分散性更好且表面积更大。结果表明，合成的纳米颗粒对大肠杆菌的抗菌活性优于金黄色葡萄球菌。此外，250 μg的AgFeO₂（Bio）和（Che） NPs的抗氧化效率分别为98%和86%。结果表明，[AgFeO₂（Bio）] NPs对人胚肾（HEK 293）细胞的细胞毒性低于[AgFeO₂（Che）] NPs。这些结果表明，[AgFeO₂（Bio）] NPs具有改善的物理化学性质，因此它们可作为生物技术中一种有效的生物催化材料。