CReSCENT：癌症单细胞表达工具包。
CReSCENT: CanceR Single Cell ExpressioN Toolkit.
机构信息
Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
出版信息
Nucleic Acids Res. 2020 Jul 2;48(W1):W372-W379. doi: 10.1093/nar/gkaa437.
CReSCENT: CanceR Single Cell ExpressioN Toolkit (https://crescent.cloud), is an intuitive and scalable web portal incorporating a containerized pipeline execution engine for standardized analysis of single-cell RNA sequencing (scRNA-seq) data. While scRNA-seq data for tumour specimens are readily generated, subsequent analysis requires high-performance computing infrastructure and user expertise to build analysis pipelines and tailor interpretation for cancer biology. CReSCENT uses public data sets and preconfigured pipelines that are accessible to computational biology non-experts and are user-editable to allow optimization, comparison, and reanalysis for specific experiments. Users can also upload their own scRNA-seq data for analysis and results can be kept private or shared with other users.
CReSCENT：癌症单细胞表达工具包（https://crescent.cloud），是一个直观且可扩展的网络门户，包含一个容器化的流水线执行引擎，用于标准化分析单细胞 RNA 测序（scRNA-seq）数据。虽然肿瘤标本的 scRNA-seq 数据很容易生成，但后续分析需要高性能计算基础设施和用户专业知识来构建分析流水线，并针对癌症生物学进行定制解释。CReSCENT 使用公共数据集和预配置的流水线，这些数据集和流水线对计算生物学非专业人员是可访问的，并且用户可编辑，以允许针对特定实验进行优化、比较和重新分析。用户还可以上传自己的 scRNA-seq 数据进行分析，结果可以保密或与其他用户共享。
Zotero 插件