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Dermatol Ther. 2020 Sep;33(5):e13430. doi: 10.1111/dth.13430. Epub 2020 Apr 30.
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J Med Virol. 2020 Sep;92(9):1634-1636. doi: 10.1002/jmv.25773. Epub 2020 Mar 27.
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BMJ. 2020 Feb 26;368:m757. doi: 10.1136/bmj.m757.
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新冠疫情爆发是否会导致皮肤慢性炎症性疾病恶化?

May COVID-19 outbreaks lead to a worsening of skin chronic inflammatory conditions?

机构信息

Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

出版信息

Med Hypotheses. 2020 Oct;143:109853. doi: 10.1016/j.mehy.2020.109853. Epub 2020 May 19.

DOI:10.1016/j.mehy.2020.109853
PMID:32492559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7236705/
Abstract

The emergence of the novel betaCoronavirus has raised serious concerns due to the virus rapid dissemination worldwide. Many areas throughout the world are now experiencing the COVID 19 outbreaks with government and policy authorities taking many aggressive isolation or restriction measures, drastically reducing also patient's visits and limiting only to the most urgent ones such as oncological visits or emergencies. Several studies have demonstrated a relationship between increased weight, obesity, diabetes, hypertension and inflammatory skin diseases. Furthermore, weight loss interventions have been shown to improve psoriasis, as well as hidradenitis suppurativa, and increase responsiveness to treatment of this conditions. We suppose that due to aggressive isolation or restriction measures, in the next future dermatologist will face with a common worsening of chronic skin inflammatory conditions due to reduced physical activities, increased intake of calories with the derived increase body weight and always more frequent treatment discontinuation. It is time to start potential preventive strategies which could limit the expected negative impact of COVID-19 related quarantine on skin diseases.

摘要

新型β冠状病毒的出现引起了严重的关注,因为该病毒在全球范围内迅速传播。目前,世界上许多地区都出现了 COVID-19 疫情爆发,政府和政策当局采取了许多积极的隔离或限制措施,这极大地减少了患者的就诊次数,只限于最紧急的就诊,如肿瘤就诊或急诊。几项研究表明,体重增加、肥胖、糖尿病、高血压和炎症性皮肤病之间存在关联。此外,体重减轻干预措施已被证明可以改善银屑病、化脓性汗腺炎,并增加对这些疾病治疗的反应性。我们假设,由于采取了积极的隔离或限制措施,在未来,皮肤科医生将面临由于体力活动减少、卡路里摄入增加导致体重增加以及治疗中断越来越频繁而导致的慢性皮肤炎症恶化的常见问题。现在是时候开始潜在的预防策略了,这些策略可能会限制 COVID-19 相关隔离对皮肤病的预期负面影响。