Institute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
National Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany.
Med Mycol. 2020 Nov 10;58(8):1187-1190. doi: 10.1093/mmy/myaa045.
Aspergillosis is the most common fungal disease of the avian respiratory tract. Due to delayed diagnosis and treatment failure, the outcome of these infections is often poor. We investigate 159 cases of avian aspergillosis among captive birds in Germany to define clinical features as well as the frequency of in vitro triazole resistance. Adult birds were more likely to present with clinical signs compared to juvenile birds, and dyspnoea was the most common clinical sign, present in 53% of birds. Molecular species identification indicated that all infections were caused by Aspergillus fumigatus. Only one of 159 independent isolates was azole resistant.
曲霉菌病是禽类呼吸道最常见的真菌病。由于诊断延误和治疗失败，这些感染的结果往往很差。我们调查了德国圈养鸟类中的 159 例鸟源曲霉菌病，以确定临床特征以及体外唑类药物耐药的频率。与幼鸟相比，成年鸟类更有可能出现临床症状，呼吸困难是最常见的临床症状，53%的鸟类存在该症状。分子种鉴定表明，所有感染均由烟曲霉引起。在 159 个独立分离株中，只有 1 株对唑类药物耐药。
