Dompe Claudia, Moncrieff Lisa, Matys Jacek, Grzech-Leśniak Kinga, Kocherova Ievgeniia, Bryja Artur, Bruska Małgorzata, Dominiak Marzena, Mozdziak Paul, Skiba Tarcio Hiroshi Ishimine, Shibli Jamil A, Angelova Volponi Ana, Kempisty Bartosz, Dyszkiewicz-Konwińska Marta
The School of Medicine, Medical Sciences and Nutrition, Aberdeen University, Aberdeen AB25 2ZD, UK.
Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznań, Poland.
J Clin Med. 2020 Jun 3;9(6):1724. doi: 10.3390/jcm9061724.
The purpose of this study is to explore the possibilities for the application of laser therapy in medicine and dentistry by analyzing lasers' underlying mechanism of action on different cells, with a special focus on stem cells and mechanisms of repair. The interest in the application of laser therapy in medicine and dentistry has remarkably increased in the last decade. There are different types of lasers available and their usage is well defined by different parameters, such as: wavelength, energy density, power output, and duration of radiation. Laser irradiation can induce a photobiomodulatory (PBM) effect on cells and tissues, contributing to a directed modulation of cell behaviors, enhancing the processes of tissue repair. Photobiomodulation (PBM), also known as low-level laser therapy (LLLT), can induce cell proliferation and enhance stem cell differentiation. Laser therapy is a non-invasive method that contributes to pain relief and reduces inflammation, parallel to the enhanced healing and tissue repair processes. The application of these properties was employed and observed in the treatment of various diseases and conditions, such as diabetes, brain injury, spinal cord damage, dermatological conditions, oral irritation, and in different areas of dentistry.
本研究的目的是通过分析激光对不同细胞的潜在作用机制，探讨激光疗法在医学和牙科应用的可能性，特别关注干细胞和修复机制。在过去十年中，激光疗法在医学和牙科应用方面的关注度显著提高。现有不同类型的激光，其使用由不同参数明确界定，如：波长、能量密度、功率输出和辐射持续时间。激光照射可对细胞和组织产生光生物调节（PBM）效应，有助于定向调节细胞行为，增强组织修复过程。光生物调节（PBM），也称为低强度激光疗法（LLLT），可诱导细胞增殖并增强干细胞分化。激光疗法是一种非侵入性方法，在促进愈合和组织修复过程的同时，有助于缓解疼痛和减轻炎症。这些特性已应用于并观察到在治疗各种疾病和病症中，如糖尿病、脑损伤、脊髓损伤、皮肤病、口腔刺激以及牙科的不同领域。
