Department of Head and Neck Oncology, HCG Cancer Hospital, Bengaluru, Karnataka, India.
Department of Head and Neck Oncology, HCG Cancer Hospital, Bengaluru, Karnataka, India.
Med Hypotheses. 2020 Nov;144:109861. doi: 10.1016/j.mehy.2020.109861. Epub 2020 May 23.
COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed.
COVID-19 已蔓延至世界上大多数国家。然而,COVID-19 在不同年龄组的表现存在一些显著差异。虽然 COVID-19 的相关数据有限,但儿童似乎不易患重病。这些独特的特征可能被认为是理解 COVID-19 中免疫系统和反应的潜在联系,并导致该疾病的有效治愈方法。我们提出了 COVID-19 中先天免疫和适应性免疫之间桥梁缺失的可能作用,并讨论了一种潜在的治疗方式。