Grajdeanu Ioana-Alina, Vata Dan, Statescu Laura, Adriana Popescu Ioana, Porumb-Andrese Elena, Ionela Patrascu Adriana, Stincanu Alina, Taranu Tatiana, Crisan Maria, Gheuca Solovastru Laura
Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, Faculty of Medicine, 700115 Iasi, Romania.
Clinic of Dermatology, Department of Dermatology, 'St. Spiridon' County Emergency Clinical Hospital, 700111 Iasi, Romania.
Exp Ther Med. 2020 Jul;20(1):78-86. doi: 10.3892/etm.2020.8620. Epub 2020 Mar 20.
Early detection of skin cancer is essential in order to obtain an improved prognosis. Clinicians need more objective and non-invasive examination methods to support their decision whether to biopsy or not tumoral lesions. These may include several imaging techniques such as dermoscopy, videodermoscopy, also known as sequential digital dermoscopy (SDD), computer-aided diagnosis (CAD), total body photography, imaging and high-frequency ultrasonography (HFUS), reflectance confocal microscopy, multiphoton tomography, electrical impedance spectroscopy, Raman spectroscopy, stepwise two-photon-laser spectroscopy and quantitative dynamic infrared. This review summarizes the current developments in the field of melanocytic lesions, such as naevi and basal cell carcinoma (BCC) imaging techniques. The aim was to collect and analyze data concerning types, indications, advantages and disadvantages of modern imaging techniques for skin tumor diagnosis. Two main methods were focused on, namely videodermoscopy and HFUS, which can be included in daily dermatologists' practice. In skin tumors HFUS allows the assessment of tumoral lesions with depth smaller than 1.5 cm, being described a correlation between ultrasonographic depth and the histologic index.
早期发现皮肤癌对于改善预后至关重要。临床医生需要更客观、非侵入性的检查方法来辅助决定是否对肿瘤性病变进行活检。这些方法可能包括多种成像技术，如皮肤镜检查、视频皮肤镜检查（也称为连续数字皮肤镜检查，SDD）、计算机辅助诊断（CAD）、全身摄影、成像及高频超声检查（HFUS）、反射式共聚焦显微镜检查、多光子断层扫描、电阻抗光谱法、拉曼光谱法、逐步双光子激光光谱法及定量动态红外技术。本综述总结了黑素细胞性病变领域的当前进展，如痣和基底细胞癌（BCC）的成像技术。目的是收集和分析有关现代成像技术用于皮肤肿瘤诊断的类型、适应证、优缺点的数据。重点关注了两种主要方法，即视频皮肤镜检查和HFUS，它们可纳入皮肤科医生的日常实践中。在皮肤肿瘤中，HFUS可用于评估深度小于1.5 cm的肿瘤性病变，超声深度与组织学指标之间存在相关性。
