Chopra Sunil, Kumar Dharmender
Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal 131039 Sonepat, Haryana, India.
Heliyon. 2020 Jun 1;6(6):e04087. doi: 10.1016/j.heliyon.2020.e04087. eCollection 2020 Jun.
Pharmaceutical and personal care products (PPCPs) are the one of sub-class under emerging organic contaminants (EOCs). Ibuprofen is the world's third most consumable drug. This drug enters into our water system through human pharmaceutical use. It attracts the attention of environmentalist on the basis of risk associated, presence and transformation in the environment. The detection and removal are the two key area where we need to focus. The concentration of such compounds in waterbodies detected through conventional and also by the advanced methods. This review we described the available technologies including chemical, physical and biological methods, etc used the for removal of Ibuprofen. The pure culture based method, mixed culture approach and activated sludge culture approach focused and pathway of degradation of ibuprofen was deciphered by using the various methods of structure determination. The various degradation methods used for Ibuprofen are discussed. The advanced methods coupled with physical, chemical, biological, chemical methods like ozonolysis, oxidation and adsorption, nanotechnology based methods, nanocatalysis and use of nonosensors to detect the presence of small amount in waterbodies can enhance the future degradation of this drug. It is necessary to develop the new detection methods to enhance the detection of such pollutants. With the developments in new detection methods based on GC-MS//MS, HPLC, LC/MS and nanotechnology based sensors makes easier detection of these compounds which can detect even very minute amount with great sensitivity and in less time. Also, the isolation and characterization of more potent microbial strains and nano-photocatalysis will significantly increase the future degradation of such harmful compounds from the environment.
药品和个人护理产品（PPCPs）是新兴有机污染物（EOCs）的一个子类。布洛芬是全球第三大消费药品。这种药物通过人类用药进入我们的水系统。基于其相关风险、在环境中的存在及转化情况，它引起了环保主义者的关注。检测和去除是我们需要关注的两个关键领域。通过传统方法以及先进方法来检测水体中此类化合物的浓度。在这篇综述中，我们描述了用于去除布洛芬的现有技术，包括化学、物理和生物方法等。重点介绍了基于纯培养的方法、混合培养方法和活性污泥培养方法，并通过各种结构测定方法解读了布洛芬的降解途径。讨论了用于布洛芬的各种降解方法。先进方法与物理、化学、生物、化学方法（如臭氧分解、氧化和吸附）、基于纳米技术的方法、纳米催化以及使用非酶传感器检测水体中少量该药物的存在相结合，可增强该药物未来的降解效果。有必要开发新的检测方法以加强对此类污染物的检测。随着基于气相色谱 - 串联质谱（GC - MS//MS）、高效液相色谱（HPLC）、液相色谱/质谱（LC/MS）和基于纳米技术的传感器等新检测方法的发展，能够更轻松地检测这些化合物，它们甚至可以在极短时间内以极高的灵敏度检测到极微量的化合物。此外，分离和鉴定更高效的微生物菌株以及纳米光催化将显著提高未来从环境中降解此类有害化合物的能力。
