Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Arch Gynecol Obstet. 2020 Sep;302(3):657-664. doi: 10.1007/s00404-020-05628-w. Epub 2020 Jun 8.
Premenstrual syndrome is a prevalent disorder affecting a large number of women in their reproductive ages. Nutritional importance of zinc has been known for a long time and studies have shown that zinc can positively affect psychological disorders.
The aim of this study was to evaluate the effects of zinc supplementation on quality of life and sleep quality of young women diagnosed with premenstrual syndrome.
This randomized, double-blind, placebo-controlled trial was carried out on 60 young university women that were allocated into two groups of intervention who took 30 mg/day of elemental zinc or placebo for three months. Pre- and post-intervention, participants completed the questionnaires of quality of life and Pittsburgh sleep quality.
After supplementation, quality of life score in the intervention group was increased (+ 9.185 ± 7.29, P < 0.001), however, in comparison with the control group, results were not significant; Physical aspects of quality of life score were significantly enhanced (+ 5.55 ± 3.71 vs. + 0.13 ± 2.87, P < 0.001). Sleep quality was marginally improved just in the zinc group (- 1.48 ± 4.12, P = 0.07).
Zinc supplementation for 12 weeks had beneficial effects on physical aspects of quality of life in young women with premenstrual syndrome.
经前期综合征是一种常见疾病，影响着育龄期大量女性。锌的营养重要性早已为人所知，研究表明锌可以对心理障碍产生积极影响。
本研究旨在评估补锌对经前期综合征年轻女性生活质量和睡眠质量的影响。
这是一项随机、双盲、安慰剂对照试验，共纳入 60 名年轻的大学女性，分为干预组和安慰剂组，干预组每天服用 30mg 元素锌，共 3 个月。在干预前后，参与者完成了生活质量和匹兹堡睡眠质量问卷。
补充后，干预组的生活质量评分增加（+9.185±7.29，P<0.001），但与对照组相比，差异无统计学意义；生活质量的生理方面评分显著提高（+5.55±3.71 比 +0.13±2.87，P<0.001）。仅在锌组睡眠质量略有改善（-1.48±4.12，P=0.07）。
补锌 12 周对经前期综合征年轻女性的生活质量生理方面有有益影响。
