青春期与默认模式网络相关的脑区成熟促进叙事理解。
Maturation of Brain Regions Related to the Default Mode Network during Adolescence Facilitates Narrative Comprehension.
作者信息
Horowitz-Kraus Tzipi, Farah Rola, Hajinazarian Ardag, Eaton Kenneth, Rajagopal Akila, Schmithorst Vincent J, Altaye Mekibib, Vannest Jennifer J, Holland Scott K
机构信息
Educational Neuroimaging Center, Faculty of Education in Science and Technology, Technion, Israel.
Reading and Literacy Discovery Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
出版信息
J Child Adolesc Behav. 2017;5(1). doi: 10.4172/2375-4494.1000328. Epub 2017 Jan 12.
OBJECTIVES
Although the Default Mode Network (DMN) has been examined extensively in adults, developmental characteristics of this network during childhood are not fully understood.
METHODS
In this longitudinal study, we characterized the developmental changes in the DMN in fifteen children who were each scanned three times during a narrative comprehension task using magnetic resonance imaging.
RESULTS
Despite similar brain-activation patterns along developmental ages 5 to 18 years when listening to stories, increased, widely distributed deactivation of the DMN was observed in children between the ages of 11 and 18 years. Our findings suggest that changes occurring with increased age, primarily brain maturation and cognitive development drive deactivation of the DMN, which in turn might facilitate attendance to the task.
CONCLUSIONS
The interpretation of our results is as a possible reference for the typical course of deactivation of the DMN and to explain the impaired patterns in this neural network associated with different language-related pathologies.
目的
尽管默认模式网络（DMN）在成年人中已得到广泛研究，但该网络在儿童期的发育特征尚未完全明确。
方法
在这项纵向研究中，我们对15名儿童在进行叙事理解任务时的默认模式网络发育变化进行了特征描述，这些儿童每人在该任务中接受了三次磁共振成像扫描。
结果
尽管在5至18岁的发育阶段，孩子们在听故事时大脑激活模式相似，但在11至18岁的儿童中观察到默认模式网络的失活增加且分布广泛。我们的研究结果表明，随着年龄增长发生的变化，主要是大脑成熟和认知发展，促使默认模式网络失活，这反过来可能有助于专注于任务。
结论
我们的研究结果解释可作为默认模式网络失活典型过程的可能参考，并用于解释与不同语言相关病理状态相关的该神经网络受损模式。
Zotero 插件