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使用高斯混合模型对2019冠状病毒病大流行进行建模与预测。

Modeling and prediction of COVID-19 pandemic using Gaussian mixture model.

作者信息

Singhal Amit, Singh Pushpendra, Lall Brejesh, Joshi Shiv Dutt

机构信息

Department of Electronics & Communication Engineering, Bennett University, Greater Noida, India.

Department of Electronics & Communication Engineering, National Institute of Technology Hamirpur, Hamirpur, India.

出版信息

Chaos Solitons Fractals. 2020 Sep;138:110023. doi: 10.1016/j.chaos.2020.110023. Epub 2020 Jun 16.

Abstract

COVID-19 is caused by a novel coronavirus and has played havoc on many countries across the globe. A majority of the world population is now living in a restricted environment for more than a month with minimal economic activities, to prevent exposure to this highly infectious disease. Medical professionals are going through a stressful period while trying to save the larger population. In this paper, we develop two different models to capture the trend of a number of cases and also predict the cases in the days to come, so that appropriate preparations can be made to fight this disease. The first one is a mathematical model accounting for various parameters relating to the spread of the virus, while the second one is a non-parametric model based on the Fourier decomposition method (FDM), fitted on the available data. The study is performed for various countries, but detailed results are provided for the India, Italy, and United States of America (USA). The turnaround dates for the trend of infected cases are estimated. The end-dates are also predicted and are found to agree well with a very popular study based on the classic susceptible-infected-recovered (SIR) model. Worldwide, the total number of expected cases and deaths are 12.7 × 10 and 5.27 × 10, respectively, predicted with data as of 06-06-2020 and 95% confidence intervals. The proposed study produces promising results with the potential to serve as a good complement to existing methods for continuous predictive monitoring of the COVID-19 pandemic.

摘要

新冠病毒病(COVID-19)由一种新型冠状病毒引起,在全球许多国家肆虐。为防止感染这种高传染性疾病,现在世界上大多数人口已在限制环境中生活了一个多月,经济活动极少。医疗专业人员在努力拯救更多人的同时,正经历一段压力巨大的时期。在本文中,我们开发了两种不同模型来捕捉病例数趋势,并预测未来几天的病例数,以便能做好适当准备来抗击这种疾病。第一个是考虑与病毒传播相关各种参数的数学模型,而第二个是基于傅里叶分解法(FDM)的非参数模型,拟合可用数据。该研究针对多个国家进行,但为印度、意大利和美利坚合众国(美国)提供了详细结果。估计了感染病例趋势的转折点日期。还预测了结束日期,发现与基于经典易感-感染-康复(SIR)模型的一项非常知名的研究结果吻合良好。在全球范围内,截至2020年6月6日的数据及95%置信区间预测,预期病例总数和死亡总数分别为12.7×10和5.27×10。本研究所提出的结果很有前景,有可能成为对现有新冠病毒病大流行持续预测监测方法的良好补充。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e17e/7296328/434405de2ab6/gr1_lrg.jpg

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