Kyoto University Health Service, Kyoto, Japan.
Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Malaysia.
Asian Pac J Cancer Prev. 2020 Jun 1;21(6):1701-1707. doi: 10.31557/APJCP.2020.21.6.1701.
This study investigated the association between intake of common alcoholic and non-alcoholic beverages and breast cancer risk among Japanese women. This study included 33,396 Japanese women aged 40-79 years from 24 areas in Japan from the Collaborative Cohort study. During the follow-up period (≥20 years), 245 incidents or mortal breast cancers were documented. Multivariable logistic regression analysis was performed to assess the independent association between breast cancer risk and the intake of Japanese green tea, coffee, and alcohol. Japanese green tea was the most commonly consumed non-alcoholic beverage (81.6% of participants), followed by coffee (34.7%) and alcohol (23.6%). No significant associations were identified between the intake of green tea and coffee with breast cancer risk (odds ratio OR 1.15, 95% confidence interval [CI] 0.82-1.60, and OR 0.84, 95% CI 0.64-1.10, respectively). Alcohol intake was associated with significant breast cancer risk (OR 1.46, 95% CI 1.11-1.92), and even infrequent alcohol consumption (.
本研究调查了日本女性摄入常见酒精性和非酒精性饮料与乳腺癌风险之间的关联。这项研究包括来自日本 24 个地区的 33396 名年龄在 40-79 岁的日本女性。在随访期间（≥20 年），记录了 245 例乳腺癌事件或死亡病例。采用多变量逻辑回归分析评估了乳腺癌风险与日本绿茶、咖啡和酒精摄入之间的独立关联。日本绿茶是最常饮用的非酒精性饮料（81.6%的参与者），其次是咖啡（34.7%）和酒精（23.6%）。绿茶和咖啡的摄入与乳腺癌风险之间没有显著关联（比值比 OR 1.15，95%置信区间 [CI] 0.82-1.60，和 OR 0.84，95% CI 0.64-1.10）。酒精摄入与显著的乳腺癌风险相关（OR 1.46，95% CI 1.11-1.92），即使是偶尔饮酒（<1 次/月）也与风险增加相关（OR 1.30，95% CI 1.01-1.68）。
