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基于计算机辅助设计/计算机辅助制造的多材料生物打印

Bioprinting of Multimaterials with Computer-aided Design/Computer-aided Manufacturing.

作者信息

Lee J M, Sing S L, Yeong W Y

机构信息

Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore.

出版信息

Int J Bioprint. 2020 Jan 22;6(1):245. doi: 10.18063/ijb.v6i1.245. eCollection 2020.

DOI:10.18063/ijb.v6i1.245
PMID:32596550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7294690/
Abstract

Multimaterials deposition, a distinct advantage in bioprinting, overcomes material's limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integrity of three-dimensional bioprinted construct. A combination of rapid cross-linking hydrogel has been chosen for the build/support setup. The bioprinted construct was further chemically cross-linked to ensure a stable construct after print. This paper also proposes a file segmentation and preparation technique to be used in bioprinting for printing freeform structures.

摘要

多材料沉积是生物打印中的一项独特优势,它克服了基于水凝胶的生物打印中材料的局限性。多材料以构建/支撑结构进行沉积,以提高三维生物打印构建体的结构完整性。已为构建/支撑设置选择了快速交联水凝胶的组合。生物打印构建体进一步进行化学交联,以确保打印后构建体的稳定性。本文还提出了一种用于生物打印自由形式结构的文件分割和准备技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/4eb1e81a3e51/IJB-6-245-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/dfbbf58ea3b1/IJB-6-245-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/f7b315198936/IJB-6-245-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/b06b12aacb76/IJB-6-245-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/5c42807f5563/IJB-6-245-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/4eb1e81a3e51/IJB-6-245-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/dfbbf58ea3b1/IJB-6-245-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/f7b315198936/IJB-6-245-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/b06b12aacb76/IJB-6-245-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/5c42807f5563/IJB-6-245-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706c/7294690/4eb1e81a3e51/IJB-6-245-g005.jpg

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