Department of Dietetics, Rijnstate Hospital, Wagnerlaan 55, Arnhem AD 6815, the Netherlands.
Department of Obstetrics and Gynaecology, Rijnstate Hospital, Wagnerlaan 55, Arnhem AD 6815, the Netherlands.
Reprod Biomed Online. 2020 Aug;41(2):317-328. doi: 10.1016/j.rbmo.2020.04.014. Epub 2020 May 15.
The success rate of medical and surgical treatment for endometriosis is limited. Empowering patients suffering from endometriosis by giving them opportunities to positively influence their symptoms could result in increased quality of life. Changing diet is one of these self-management activities, but current endometriosis diets are mostly based on limited evidence. In order to gain more insight into the role of nutrients on symptoms in women with endometriosis a systematic review was carried out in which the effect of a nutrient or diet on endometriosis-related symptoms was investigated. PubMed and the Cochrane Database of Systematic Reviews were searched for relevant articles up to 1 March 2019. Search terms included endometriosis, diet, and 26 possible nutrients were identified after assessing available endometriosis diets in the literature and on the internet. Twelve studies were included. Study quality, including risk of bias, was assessed using GRADE criteria and all were of low to very low quality. Intake of additional fatty acids, antioxidants and a combination of vitamins and minerals may have a positive effect on endometriosis-associated symptoms. Future studies are necessary to gain evidence about which food products are effective and in which amounts.
医学和手术治疗子宫内膜异位症的成功率有限。通过让子宫内膜异位症患者有机会积极影响其症状来赋予他们力量，可以提高生活质量。改变饮食是这些自我管理活动之一，但目前的子宫内膜异位症饮食大多基于有限的证据。为了更深入地了解营养对子宫内膜异位症妇女症状的作用，进行了系统评价，其中研究了营养素或饮食对与子宫内膜异位症相关的症状的影响。检索了 PubMed 和 Cochrane 系统评价数据库，以获取截至 2019 年 3 月 1 日的相关文章。检索词包括子宫内膜异位症、饮食和 26 种可能的营养素，这些营养素是在评估文献和互联网上现有的子宫内膜异位症饮食后确定的。纳入了 12 项研究。使用 GRADE 标准评估研究质量，包括偏倚风险，所有研究的质量均为低到极低。摄入额外的脂肪酸、抗氧化剂以及维生素和矿物质的组合可能对与子宫内膜异位症相关的症状有积极影响。需要进一步的研究来获得有关哪些食物有效以及有效剂量的证据。
