Independent Laboratory of Minimally Invasive Gynaecology and Gynaecological Endocrinology, Medical University of Lublin, Staszica 16 St., 20-081 Lublin, Poland.
Department of Experimental Immunology, Medical University of Lublin, Chodźki 4a St., 20-093 Lublin, Poland.
Nutrients. 2024 Jan 2;16(1):154. doi: 10.3390/nu16010154.
Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue in ectopic locations. Since the treatment options for this disease are still limited, and the cure rate is unsatisfactory, the search for ways to treat symptoms and modify the course of the disease is of key importance in improving the quality of life of patients with endometriosis. So far, the literature has shown that nutrition can influence endometriosis through hormonal modification and altering the inflammatory or oxidative response. Since the importance of nutrition in this disease is still a subject of scientific research, we aimed to summarize the current knowledge on the role of dietary modifications in endometriosis. Our review showed that nutrients with anti-inflammatory and antioxidant properties, including most vitamins and several trace elements, may influence the pathogenesis of endometriosis and can be considered as the nutrients preventing the development of endometriosis. However, despite the many discoveries described in this review, further interdisciplinary research on this topic seems to be extremely important, as in the future, it may result in the development of personalized therapies supporting the treatment of endometriosis.
子宫内膜异位症是一种慢性、激素依赖性疾病，其特征是子宫内膜组织出现在异位部位。由于这种疾病的治疗选择仍然有限，治愈率也不尽如人意，因此寻找治疗症状和改变疾病进程的方法对于提高子宫内膜异位症患者的生活质量至关重要。到目前为止，文献表明，营养可以通过激素调节和改变炎症或氧化反应来影响子宫内膜异位症。由于营养在这种疾病中的重要性仍然是一个科学研究的课题，我们旨在总结饮食改变在子宫内膜异位症中的作用的现有知识。我们的综述表明，具有抗炎和抗氧化特性的营养素，包括大多数维生素和几种微量元素，可能影响子宫内膜异位症的发病机制，可以被认为是预防子宫内膜异位症发展的营养素。然而，尽管在这篇综述中描述了许多发现，进一步的跨学科研究似乎是极其重要的，因为未来它可能会开发出个性化的治疗方法，支持子宫内膜异位症的治疗。
