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痴呆症神经行为症状的临床方面

Clinical Aspects of Neurobehavioral Symptoms of Dementia.

作者信息

Yang YoungSoon, Kandiah Nagaendran, Kim SangYun, Kwak Yong Tae

机构信息

Department of Neurology, Duke-NUS Singapore, National Neuroscience Institute, Singapore.

Department of Neurology, Seoul National University College of Medicine & Neurocognitive Behavior Center, Seoul National University Bundang Hospital, Seongnam, Korea.

出版信息

Dement Neurocogn Disord. 2020 Jun;19(2):54-64. doi: 10.12779/dnd.2020.19.2.54.

DOI:10.12779/dnd.2020.19.2.54
PMID:32602280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7326614/
Abstract

Neurobehavioral symptoms of dementia (NBSD) are very common and are significant symptoms of the illness, contributing most to caregiver burdens and often resulting in premature institutionalization of the person with dementia. The main symptoms of NBSD are anxiety, depression, delusions, and hallucinations. NBSD produce significant problems for both patients and caregivers. The pathophysiology of NBSD is determined by genetic, structural, or environmental factors. Therefore, treatment of NBSD requires continuous and organic cooperation between patients, caregivers, social environments, and doctors. Therefore, it is important for neurologists, who mainly view NBSD for dementia patients, to increase their understanding of these more comprehensive areas as well as the latest insights and treatments to help patients and caregivers.

摘要

痴呆的神经行为症状(NBSD)非常常见,是该疾病的重要症状,对照护者负担影响最大,且常常导致痴呆患者过早入住机构。NBSD的主要症状包括焦虑、抑郁、妄想和幻觉。NBSD给患者和照护者都带来了重大问题。NBSD的病理生理学由遗传、结构或环境因素决定。因此,NBSD的治疗需要患者、照护者、社会环境和医生之间持续且有机的合作。所以,对于主要诊治痴呆患者NBSD的神经科医生而言,增进对这些更广泛领域以及最新见解和治疗方法的了解,以帮助患者和照护者,是很重要的。

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Misidentification Delusions: Prevalence in Different Types of Dementia and Validation of a Structured Questionnaire.错误识别妄想:在不同类型痴呆症中的患病率及一份结构化问卷的验证
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Psychosis in Alzheimer's disease is associated with frontal metabolic impairment and accelerated decline in working memory: findings from the Alzheimer's Disease Neuroimaging Initiative.阿尔茨海默病中的精神病与额叶代谢受损及工作记忆加速衰退有关:来自阿尔茨海默病神经影像学倡议的研究结果。
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