Metabolism, Nutrition, and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Londrina, PR, Brazil.
Department of Physical Education, Federal University of Sergipe, São Cristovão, SE, Brazil.
Arch Gerontol Geriatr. 2020 Sep-Oct;90:104156. doi: 10.1016/j.archger.2020.104156. Epub 2020 Jun 15.
This study aimed to investigate the relationship between crude bioimpedance variables with bone mineral density (BMD) in older adults.
One hundred eighty-four older men and women (≥ 60 years old) composed the sample. BMD (whole-body) was measured through dual-energy X-ray absorptiometry. Bioimpedance spectroscopy was used to estimate whole-body resistance and reactance as well as to calculate the phase angle (PhA) and fat-free mass (FFM). Age, gender, body mass, FFM, height, calcium intake, vitamin D intake, number of fractures, number of diseases, and number of medications were included as covariates in the regression analyses.
BMD fractions were significantly (P < 0.01) associated with PhA (femur: r = 0.524; neck: r = 0.450; and forearm: r = 0.437). Independently of age, body mass, FFM, calcium intake, vitamin D, number of diseases, fratures and medications, PhA remains a significant explanator of the variability of total (β = 0.22; P < 0.001), femur (β = 0.10; P = 0.018), and neck BMD (β = 0.07; P = 0.05) for men, and total (β = 0.08; P = 0.002), femur (β = 0.06; P = 0.005), neck (β = 0.04; P = 0.03), and forearm BMD (β = 0.05; P = 0.004) for women.
Our results suggest that a higher PhA is associated with BMD in older men and women fractions regardless of relevant covariates highlighting the biological meaning of this simple and crude bioimpedance-based measure in the elderly population.
本研究旨在探讨老年人粗生物阻抗变量与骨密度（BMD）之间的关系。
本研究纳入了 184 名年龄在 60 岁及以上的老年人。采用双能 X 射线吸收法测量全身骨密度（BMD）。生物阻抗谱用于估计全身电阻和电抗，并计算相位角（PhA）和去脂体重（FFM）。在回归分析中，年龄、性别、体重、FFM、身高、钙摄入量、维生素 D 摄入量、骨折次数、疾病数量和用药数量被纳入协变量。
BMD 分数与 PhA 显著相关（P < 0.01）（股骨：r = 0.524；颈：r = 0.450；前臂：r = 0.437）。独立于年龄、体重、FFM、钙摄入量、维生素 D、疾病数量、骨折和用药，PhA 仍然是总（β= 0.22；P < 0.001）、股骨（β= 0.10；P = 0.018）和颈 BMD（β= 0.07；P = 0.05）的显著解释变量，对于男性，以及总（β= 0.08；P = 0.002）、股骨（β= 0.06；P = 0.005）、颈（β= 0.04；P = 0.03）和前臂 BMD（β= 0.05；P = 0.004）对于女性。
我们的结果表明，较高的 PhA 与老年人各部位 BMD 相关，无论相关协变量如何，这突出了这种简单而粗糙的基于生物阻抗的测量方法在老年人群中的生物学意义。
