Pandey Saurabh, Yadav Bharat, Pandey Arvind, Tripathi Takshashila, Khawary Masuma, Kant Sashi, Tripathi Deeksha
Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi-110062, India.
Microbial Pathogenesis and Microbiome Lab, Department of Microbiology, Central University of Rajasthan, Ajmer, Rajasthan-305817, India.
Biology (Basel). 2020 Jun 26;9(6):141. doi: 10.3390/biology9060141.
The COVID-19 pandemic is rising at an unprecedented rate. The surging number of deaths every day, global lockdown and travel restrictions have resulted in huge losses to society. The impact is massive and will leave a historical footprint. The Spanish Flu of 1918, which was the last pandemic that had a similar impact, was shadowed under the consequences of World War I. All the brilliance, strength and economies of countries worldwide are aimed at fighting the COVID-19 pandemic. The knowledge about coronavirus dynamics, its nature and epidemiology are expanding every day. The present review aims to summarize the structure, epidemiology, symptoms, statistical status of the disease status, intervention strategies and deliberates the lessons learnt during the pandemic. The intervention approaches, antiviral drug repurposing and vaccine trials are intensified now. Statistical interpretations of disease dynamics and their projections may help the decision-makers.
新冠疫情正以前所未有的速度蔓延。每日激增的死亡人数、全球封锁和旅行限制给社会造成了巨大损失。其影响巨大，将留下历史印记。1918年的西班牙大流感是上一次造成类似影响的大流行，当时处于第一次世界大战的阴影之下。全世界各国所有的智慧、力量和经济都致力于抗击新冠疫情。关于冠状病毒动态、其性质和流行病学的知识每天都在扩展。本综述旨在总结该疾病的结构、流行病学、症状、疾病状态的统计情况、干预策略，并探讨疫情期间吸取的教训。目前正在加强干预方法、抗病毒药物的重新利用和疫苗试验。对疾病动态及其预测的统计解读可能会对决策者有所帮助。
