Arnesen Erik Kristoffer, Christensen Jacob Juel, Andersen Rikke, Eneroth Hanna, Erkkola Maijaliisa, Høyer Anne, Lemming Eva Warensjö, Meltzer Helle Margrete, Halldórsson Þórhallur Ingi, Þórsdóttir Inga, Schwab Ursula, Trolle Ellen, Blomhoff Rune
Department of Nutrition, University of Oslo, Oslo, Norway.
Norwegian National Advisory Unit on Familial Hypercholesterolemia, Oslo University Hospital, Oslo, Norway.
Food Nutr Res. 2020 Jun 18;64. doi: 10.29219/fnr.v64.4403. eCollection 2020.
Qualified systematic reviews (SRs) will form the main basis for evaluating causal effects of nutrients or food groups on health outcomes in the sixth edition of Nordic Nutrition Recommendations to be published in 2022 (NNR2022).
To describe rationale and structure of SRs used in NNR2022.
The SR methodologies of the previous edition of NNR were used as a starting point. Methodologies of recent SRs commissioned by leading national food and health authorities or international food and health organizations were examined and scrutinized. Methodologies for developing SRs were agreed by the NNR2022 Committee in a consensus-driven process.
Qualified SRs will be developed by a cross-disciplinary group of experts and reported according to the requirements of the EQUATOR network. A number of additional requirements must also be fulfilled, including 1) a clearly stated set of objectives and research questions with pre-defined eligibility criteria for the studies, 2) an explicit, reproducible methodology, 3) a systematic search that attempts to identify all studies that would meet the eligibility criteria, 4) an assessment of the validity of the findings of the included studies through an assessment of 'risk of bias' of the studies, 5) a systematic presentation and synthesis of the characteristics and findings of the included studies, and 6) a grading of the overall evidence. The complete definition and requirements of a qualified SR are described.
Most SRs published in scientific journals do not fulfill all criteria of the qualified SRs in the NNR2022 project. This article discusses the structure and rationale for requirements of qualified SRs in NNR2022. National food and health authorities have only recently begun to use qualified SRs as a basis for nutrition recommendations.
Qualified SRs will be used to inform dietary reference values (DRVs) and food-based dietary guidelines (FBDGs) in the NNR2022 project.
合格的系统评价（SRs）将成为2022年即将出版的《北欧营养建议》第六版（NNR2022）中评估营养素或食物组对健康结果因果效应的主要依据。
描述NNR2022中使用的SRs的基本原理和结构。
以前版本的NNR的SR方法作为起点。对由主要国家食品和卫生当局或国际食品和卫生组织委托进行的近期SR的方法进行了检查和审查。制定SRs的方法由NNR2022委员会在一个以共识为驱动的过程中达成一致。
合格的SRs将由一个跨学科专家小组制定，并根据EQUATOR网络的要求进行报告。还必须满足一些额外的要求，包括1）一套明确阐述的目标和研究问题，以及针对研究的预先定义的纳入标准，2）一种明确的、可重复的方法，3）一次系统的检索，试图识别所有符合纳入标准的研究，4）通过评估研究的“偏倚风险”来评估纳入研究结果的有效性，5）对纳入研究的特征和结果进行系统的呈现和综合，以及6）对整体证据进行分级。描述了合格SR的完整定义和要求。
科学期刊上发表的大多数SRs不符合NNR2022项目中合格SRs的所有标准。本文讨论了NNR2022中合格SRs要求的结构和基本原理。国家食品和卫生当局直到最近才开始将合格的SRs用作营养建议的依据。
合格的SRs将用于为NNR2022项目中的膳食参考值（DRVs）和基于食物的膳食指南（FBDGs）提供信息。
