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本文引用的文献

1
A fast and sensitive activity assay for lytic polysaccharide monooxygenase.一种用于裂解多糖单加氧酶的快速灵敏活性测定方法。
Biotechnol Biofuels. 2018 Mar 23;11:79. doi: 10.1186/s13068-018-1063-6. eCollection 2018.
2
An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion.一个古老的裂解多糖单加氧酶家族,在节肢动物发育和生物质消化中发挥作用。
Nat Commun. 2018 Feb 22;9(1):756. doi: 10.1038/s41467-018-03142-x.
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Lytic xylan oxidases from wood-decay fungi unlock biomass degradation.木质腐朽真菌的溶木聚糖氧化酶可打开生物质降解之门。
Nat Chem Biol. 2018 Mar;14(3):306-310. doi: 10.1038/nchembio.2558. Epub 2018 Jan 29.
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Oxidative cleavage of polysaccharides by monocopper enzymes depends on HO.单铜酶通过 HO 实现多糖的氧化裂解。
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Boosting LPMO-driven lignocellulose degradation by polyphenol oxidase-activated lignin building blocks.通过多酚氧化酶激活的木质素构建单元促进LPMO驱动的木质纤维素降解
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Structural diversity of lytic polysaccharide monooxygenases.溶菌多糖单加氧酶的结构多样性。
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Lignocellulose degradation mechanisms across the Tree of Life.生命之树上的木质纤维素降解机制。
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Lytic Polysaccharide Monooxygenases in Biomass Conversion.溶细胞多糖单加氧酶在生物质转化中的作用。
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10
Discovery of the combined oxidative cleavage of plant xylan and cellulose by a new fungal polysaccharide monooxygenase.新型真菌多糖单加氧酶对植物木聚糖和纤维素的联合氧化断裂作用的发现。
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木质纤维素降解:参与木质纤维素降解的真菌及真菌酶概述

Lignocellulose degradation: An overview of fungi and fungal enzymes involved in lignocellulose degradation.

作者信息

Andlar Martina, Rezić Tonči, Marđetko Nenad, Kracher Daniel, Ludwig Roland, Šantek Božidar

机构信息

Department of Biochemical Engineering Faculty of Food Technology and Biotechnology University of Zagreb Zagreb Croatia.

Department of Food Sciences and Technology University of Natural Resources and Life Sciences Vienna Austria.

出版信息

Eng Life Sci. 2018 Jun 27;18(11):768-778. doi: 10.1002/elsc.201800039. eCollection 2018 Nov.

DOI:10.1002/elsc.201800039
PMID:32624871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6999254/
Abstract

This review aims to present current knowledge of the fungi involved in lignocellulose degradation with an overview of the various classes of lignocellulose-acting enzymes engaged in the pretreatment and saccharification step. Fungi have numerous applications and biotechnological potential for various industries including chemicals, fuel, pulp, and paper. The capability of fungi to degrade lignocellulose containing raw materials is due to their highly effective enzymatic system. Along with the hydrolytic enzymes consisting of cellulases and hemicellulases, responsible for polysaccharide degradation, they have a unique nonenzymatic oxidative system which together with ligninolytic enzymes is responsible for lignin modification and degradation. An overview of the enzymes classification is given by the Carbohydrate-Active enZymes (CAZy) database as the major database for the identification of the lignocellulolytic enzymes by their amino acid sequence similarity. Finally, the recently discovered novel class of recalcitrant polysaccharide degraders-lytic polysaccharide monooxygenases (LPMOs) are presented, because of these enzymes importance in the cellulose degradation process.

摘要

本综述旨在介绍目前关于参与木质纤维素降解的真菌的知识,并概述参与预处理和糖化步骤的各类木质纤维素作用酶。真菌在包括化工、燃料、纸浆和造纸等多个行业有众多应用和生物技术潜力。真菌降解含木质纤维素原料的能力归因于其高效的酶系统。除了由负责多糖降解的纤维素酶和半纤维素酶组成的水解酶外,它们还有独特的非酶氧化系统,该系统与木质素分解酶一起负责木质素的修饰和降解。碳水化合物活性酶(CAZy)数据库给出了酶分类的概述,该数据库是通过氨基酸序列相似性鉴定木质纤维素分解酶的主要数据库。最后,介绍了最近发现的新型难降解多糖降解酶——裂解多糖单加氧酶(LPMO),因为这些酶在纤维素降解过程中具有重要作用。