Rychen Guido, Aquilina Gabriele, Azimonti Giovanna, Bampidis Vasileios, Bastos Maria de Lourdes, Bories Georges, Chesson Andrew, Cocconcelli Pier Sandro, Flachowsky Gerhard, Gropp Jürgen, Kolar Boris, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Mayo Baltasar, Ramos Fernando, Saarela Maria, Villa Roberto Edoardo, Wallace Robert John, Wester Pieter, Martelli Giovanna, Renshaw Derek, López-Gálvez Gloria, Mantovani Alberto
EFSA J. 2018 Mar 8;16(3):e05210. doi: 10.2903/j.efsa.2018.5210. eCollection 2018 Mar.
The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked by the European Commission to deliver a scientific opinion on the safety and efficacy of benzoic acid as feed flavouring for piglets (suckling, weaned), pigs for fattening, sows (for reproduction, in order to have benefit in piglets), minor porcine species, chickens (for fattening, reared for laying), hens (laying, breeding), turkeys (for fattening, for breeding purposes, reared for breeding) and minor poultry species. Benzoic acid is safe for weaned piglets at 2,500 mg/kg feed, and for laying hens, turkeys and chickens for fattening at 500 mg/kg feed; no conclusions could be drawn for suckling piglets and sows. The conclusions on weaned piglets can be extended to pigs for fattening and extrapolated to growing minor porcine species. The conclusions on chickens/turkeys for fattening can be extended to chickens reared for laying and turkeys reared for breeding and extrapolated to minor poultry species up to the point of lay. In the absence of safety margin in laying hens, no conclusions can be reached for minor poultry species for laying/breeding. The use of the additive is not expected to pose a risk to consumer, considering that the additive is rapidly metabolised with very low deposition, if any, in edible tissues of pigs and poultry and that foods of animal origin provide a very minor contribution, if any, to the overall dietary intake of benzoic acid. Owing to the unlikelihood of exposure, no risk to users upon inhalation of the additive is expected; the additive is not a skin sensitiser, but is a skin/ eye irritant. The proposed use of the additive does not pose environmental risks. Benzoic acid is authorised as food flavouring and its function in feed is essentially the same; no further demonstration of efficacy is necessary.
动物饲料添加剂及产品或物质专家委员会（FEEDAP）应欧盟委员会要求，就苯甲酸作为仔猪（哺乳仔猪、断奶仔猪）、育肥猪、母猪（用于繁殖，以使仔猪受益）、小型猪种、肉鸡（用于育肥、饲养产蛋）、蛋鸡（产蛋、育种）、火鸡（用于育肥、育种、饲养繁殖）和小型家禽品种的饲料调味剂的安全性和有效性发表科学意见。苯甲酸在饲料中添加量为2500毫克/千克时对断奶仔猪是安全的，在饲料中添加量为500毫克/千克时对产蛋母鸡、火鸡和育肥鸡是安全的；对于哺乳仔猪和母猪无法得出结论。关于断奶仔猪的结论可扩展至育肥猪，并外推至生长中的小型猪种。关于育肥鸡/火鸡的结论可扩展至饲养产蛋的鸡和饲养繁殖的火鸡，并外推至产蛋前的小型家禽品种。由于产蛋母鸡没有安全边际，因此对于产蛋/育种的小型家禽品种无法得出结论。考虑到该添加剂在猪和家禽的可食用组织中迅速代谢且沉积量极低（若有沉积），并且动物源性食品对苯甲酸的总体膳食摄入量贡献极小（若有贡献），预计该添加剂的使用不会对消费者构成风险。由于不太可能接触到，预计吸入该添加剂对使用者没有风险；该添加剂不是皮肤致敏剂，但具有皮肤/眼睛刺激性。拟议的添加剂使用不会造成环境风险。苯甲酸被批准用作食品调味剂，其在饲料中的功能基本相同；无需进一步证明其有效性。
