Wu Wen-Guang, Dong Lin-Lin, Chen Shi-Lin
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2020 Jun;45(11):2714-2719. doi: 10.19540/j.cnki.cjcmm.20200329.105.
To breed new varieties of medicinal plants with high resistance is the premise to ensure the production of high-quality medicinal materials. Molecular breeding using modern molecular biology and genetic technology can save time and effort and realize rapid and accurate breeding. Here we are trying to summarize the difference of breeding characteristics between medicinal plants and crops such as genetic background and breeding purpose. The strategy of molecular breeding of medicinal plants was summarized, and the four-phases breeding based on high-throughput sequencing and target gene mining was emphasized. We put forward the current molecular breeding of medicinal plants in the condition of four phases breeding is the optimal technological way of breeding, and gene editing breeding is the direction of medicinal plants breeding.
培育具有高抗性的药用植物新品种是确保优质药材生产的前提。利用现代分子生物学和遗传技术进行分子育种可以省时省力，实现快速准确的育种。在此，我们试图总结药用植物与农作物在育种特性上的差异，如遗传背景和育种目的。总结了药用植物分子育种的策略，并强调了基于高通量测序和目标基因挖掘的四阶段育种。我们提出，在四阶段育种条件下进行当前的药用植物分子育种是最佳的育种技术途径，基因编辑育种是药用植物育种的方向。
