Helbo-Hansen S, Westergaard V, Krogh B L, Svendsen H P
Odense University Hospital, Department of Anaesthesiology, Denmark.
Acta Anaesthesiol Scand. 1988 Aug;32(6):502-4. doi: 10.1111/j.1399-6576.1988.tb02774.x.
The effects of addition of 1 ml of lignocaine (10 mg) or isotonic saline to 19 ml of the emulsified preparation of propofol (Diprivan) were studied in a randomised, double-blind trial in 80 patients. The incidence and severity of pain on injection of propofol were significantly reduced by the addition of lignocaine (P less than 0.01).
在一项针对80名患者的随机双盲试验中，研究了向19毫升丙泊酚乳剂（得普利麻）中添加1毫升利多卡因（10毫克）或等渗盐水的效果。添加利多卡因可显著降低丙泊酚注射时疼痛的发生率和严重程度（P<0.01）。
